Abstract：Objective To explore the incidence rate and risk factors of children Kawasaki disease (KD) complication with coronary artery lesion (CAL). Methods Totally 283 children with KD were retrospectively investigated, and they were divided into the CAL group and the NCAL group according to the occurrence of coronary artery disease. The incidence rate of CAL in children with KD was described, and the high risk factors of CAL in children with KD were screened by χ2 test and multiple factors logistic regression methods. Results The incidence rate of CAL in 283 children with KD was 31.10%. The risk factors of CAL in children with KD included heating time (OR=2.818), delayed diagnosis and treatment (OR=3.459), hs-CRP (OR=3.815), erythrocyte sedimentation rate (OR=4.031), cTnI (OR=5.618) and IVIG resistance (OR=4.618). Conclusion Children KD have a high incidence rate of CAL. To aim directly at these above high risk factors, we should early screen, diagnose and treat children with KD, to cut down the incidence rate of CAL, and improve the prognosis of children with KD.
