Abstract：Objective To review and analyze the death cases from 2003 to 2018 in a tertiary hospital, to find out the basic situation of the death cases, the main causes of death and the related expenses, in order to provide reference for diagnosis and treatment of the disease , and reduce the case fatality rate. Methods The total number of inpatients from 2003 to 2018 was collected from the hospital medical record information system, and the data of 6 833 inpatients who died in the hospital were analyzed by using Excel 2007 and SPSS 19.0 softwares. Results From 2003 to 2018, the total number of inpatients was 404 076, and 6 833 patients died, with the case fatality rate 1.69%. The death cases have been increasing year by year in the past 16 years, but the fatality rate has been decreasing year by year. The highest mortality rate was 6.18% in the group aged over 81, followed by 4.06% in the group aged 71～80, and the highest mortality ratio was 21.04% in the group aged 61～70, followed by 21.03% in the group aged 71～80. There was a significant difference in mortality among different age groups (χ2=4071.81, P< 0.01). The mortality rate of male (2.16%) was significantly higher than that of female (1.22%) with significant statistical difference (χ2=540.16, P<0.01). Tumors, cardiovascular diseases, respiratory diseases, gastrointestinal diseases, poisoning and external causes were the main causes of death, accounting for 89.56 % of the total number of deaths. The top 10 leading causes of death were lung cancer, liver cancer, stomach cancer, brain hemorrhage, breast cancer, colon cancer, brain injury, pneumonia, cerebral infarction and nasopharyngeal carcinoma. The total cost of hospitalization has increased 31.46% in the past 16 years. The hospital stays and rescue times have impacted the total cost, and the proportion of drugs has decreased every year since 2011. Conclusion From 2003 to 2018, most of the patients who died in the hospital were middle-aged and elderly male patients. Tumor and cardiovascular disease were the main disease causes of death. Lung Cancer, liver cancer and stomach cancer were the main disease types causing death. The average hospitalization cost increased every year, and in proportion to the hospital stays and rescue times. The relevant departments of hospitals should rationally allocate medical resources, strengthen the subject construction of tumor, circulatory system and respiratory disease, to reduce the mortality rate of patients, control the hospital stays, carry out reasonable rescue and control the total hospitalization expenses.
［15］FEDERICO PINERO, SEBASTIAN MARCIANO, NORA FERNANDEZET, et al. Intermediateadvanced hepatocellular carcinoma in Argentina: Treatment and survival analysis［J］. World Journal of Gastroenterology，2019，25（27）：3607-3618.
