Abstract：Objective To analyze the clinical features and the application effect of PICC catheter chemotherapy in patients with nasopharyngeal carcinoma in Wenzhou.Methods Totally 840 patients with nasopharyngeal carcinoma from October 2015 to May 2017 in Wenzhou were selected for the study. The clinical characteristics of the patient's onset age, pathological classification, lymph node metastasis, nasal symptoms and ear symptoms were statistically discussed. Then, according to the random table method, 840 cases patients were randomly divided into the observation group (n=420) and the control group (n=420). The observation group was given PICC catheter for chemotherapy and healthy education, the control group was treated with shallow intravenous indwelling needle for chemotherapy, and the incidence of postoperative adverse complications was recorded in two groups.Results The incidence of nasopharyngeal cancer gradually increased with age and the highest incidence rate was 60.59% for patients aged 40 to under 60 years old. There were 755 cases of squamous cell carcinoma, 26 cases of vesicular nucleus carcinoma and 59 cases of undifferentiated carcinoma. The incidence of various clinical symptoms was 66.07% of cervical lymph node metastasis, 56.67% of the nose symptoms, 12.02% of ear symptoms, 30.05% headache, 19.64% cranial nerve injury, and 4.05% distant metastasis. 42.05% cases presented only one symptom when diagnosed. After chemotherapy, the incidence of adverse complications in the observation group was 5.48%, significantly lower than the 26.43% of the control group, and the difference was statistically significant (P<0.05).Conclusion Squamous cell carcinoma is the main type of nasopharyngeal carcinoma and the clinical characteristics of nasopharyngeal carcinoma are atypical. PICC catheter chemotherapy can reduce the incidence of adverse complications, improve the quality of life of patients, and is worthy of clinical application.
陈小芳, 孔丽敏, 杨玉燕. 温州地区鼻咽癌化疗PICC置管患者临床特点及健康教育分析[J]. 中国医院统计, 2018, 25(6): 441-443.
Chen Xiaofang, Kong Limin, Yang Yuyan. Clinical features and health education analysis of patients with chemotherapy by PICC of nasopharyngeal carcinoma in Wenzhou. journal1, 2018, 25(6): 441-443.
