Abstract：Objective To explore the characteristics and risk factors of nosocomial infection of burn patients, and to provide prevention strategy for it.Methods Totally 376 burn inpatients were investigated retrospectively, and they were divided into the infection group (n=89) and the non-infection group (n=287) according to nosocomial infection. The incidence rate and sites of nosocomial infection were described, and the high risk factors of nosocomial infection were screened by single factor comparison method and multiple factors logistic regression method.Results The incidence rate of nosocomial infection in these 376 burn inpatients was 23.67% (89/376), and the sites of infection were mainly in wound infection (59.55%) and respiratory tract infection (21.35%). Multiple factor analysis result showed that the independent risk factors of nosocomial infection of burn patients included concomitant underlying diseases (OR=2.459, 95%CI:1.513～3.998), area of burn (OR=3.435, 95%CI:2.090～5.647), invasive operation (OR=3.778, 95%CI:2.097～6.807), use of multiple antibiotics (OR=7.040, 95%CI:4.240～11.688), hypoproteinemia (OR=5.173, 95%CI:3.165～8.455) and residual wound (OR=4.755, 95%CI:2.660～8.501).Conclusion The incidence of nosocomial infection is relatively high in burn patients. We should adopt prevention measures such as strengthening nutritional support, raising organism immunity, elimination of residual wounds and scarring, rational use of antibiotics, and strict implementation of aseptic operation, to gradually cut down the incidence rate of nosocomial infection of burn patients.
