Abstract：Objective To analyze the risk factors of type 2 diabetes mellitus complicated with diabetic retinopathy (DR) in Wenzhou city, and to provide reference for clinical prevention and treatment.Methods Totally 864 patients with type 2 diabetes who were examined from January 2016 to April 2018 in Wenzhou City were enrolled. According to the presence or absence of DR lesions, they were divided into the DR group including 263 patients and the non-DR group including 601 patients. The general clinical data and laboratory data of all patients were collected to analyze the epidemiology and risk factors of type 2 diabetes complicated with diabetic retinopathy.Results Two hundred and sixty-three cases with diabetic retinopathy were detected in 864 patients with type 2 diabetes, and the detection rate was 30.4%. The prevalence rates of male and female were 28.7% and 33.3%. The incidences of DR in patients with diabetes aged under 50, from 50 to under 60, from 60 to under 70, 70 and above were 25.0%, 26.0%, 44.5%, and 35.1% respectively. The incidences of DR in the course of diabetes under 5 years, from 5 to under 15 years, 15 and above years were 12.2%, 36.7%, and 63.8% respectively. The multivariate analysis showed that age, course of disease, family history, DBP, FBG, HbA1c, and ALB were independent risk factors for type 2 diabetes mellitus complicated with diabetic retinopathy with statistical significant difference (P<0.05).Conclusion Among patients with type 2 diabetes in Wenzhou City, the risk of diabetic retinopathy is high, and DR is closely related to age, course of disease, family history, blood pressure, FBG, HbA1c, and ALB levels. It is suggested that effective intervention should be taken to prevent the occurrence of DR in patients with type 2 diabetes at risk.
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