Abstract：Objective To explore the high risk factors of prognosis death of acute ischemic stroke population, and evaluate the effects of these high risk factors screening of acute ischemic stroke. Methods Two hundred and twelve patients with cute ischemic stroke were divided into survival group and death group according to whether death or not after one-year discharge from the hospital. Single factor was compared between both groups. With multiple factors method we screened independent risk factors, and analyzed diagnostic effects with BNP and NIHSS score screening prognosis of acute ischemic stroke. Results The death rate of prognosis of acute ischemic stroke in the duration of hospital stay was 15.09% (32/212). Multiple risk factors analysis result showed that atrial fibrillation (OR=3.819), cerebral infarction of a large area (OR=6.228), BNP of blood plasma (OR=5.191) and NIHSS score (OR=3.536) were the independent risk factors of prognosis death of acute ischemic stroke. The sensitivity, specificity and accuracy of NIHSS score screening prognosis were respectively 90.6%, 75.0% and 77.4%, and those of BNP were respectively 84.4%, 81.7% and 82.1%. Conclusion These factors of atrial fibrillation, cerebral infarction of a large area, BNP of blood plasma and NIHSS score are the independent risk factors of prognosis death of acute ischemic stroke. Of the total, BNP of blood plasma and NIHSS score could be predictive indexes of prognosis death of acute ischemic stroke.
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