Abstract：Objective To explore correlated risk factors of hyperbilirubinemia of neonate patients, and provide basis for preventing hyperbilirubinemia of neonate. Methods One hundred and eighty neonates with hyperbilirubinemia were classified as case group, and 180 healthy neonates were classified as control group. With Case-control study method, single factor was respectively compared between the two groups, and the risk factors of hyperbilirubinemia of neonates were screened by multiple factors logistic regression method. Results Multiple factors logistic regression analysis results showed that the factors of fetal age (OR=4.019), complication of fetation (OR=4.080), fetal distress (OR=1.865), infection (OR=3.277), HIE (OR=2.689) and score of 1 min Apgar (OR=5.249) were all the risk factors of hyperbilirubinemia of neonates. Conclusion The high risk factors of hyperbilirubinemia of neonate included premature birth, complication of fetation, fetal distress, infection, HIE and low Apgar. We should think highly of antenatal examination and the detection of postpartum bilirubin, and take the necessary intervention measures for high risk factors.
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