Abstract：Objective To explore the correlated risk factors of rotavirus (RV) enteritis complicated with myocardial damage of children, and to provide basis for early diagnosing and treating RV enteritis complicated with myocardial damage. Methods With case-control study method, we collected 213 cases of RV enteritis complicated with myocardial damage of children as case group, and 159 cases of RV enteritis without myocardial damage of children as control group, with multiple logistic Regression analysis method to screen the risk factors of RV enteritis complicated with myocardial damage. Results The incidence rate of RV enteritis complicated with myocardial damage was 57.3% (213/372). Single factor analysis indicated that age, hyperpyrexia, diarrhea, dehydration, acidosis, electrolyte disturbances and electrocardiographic abnormality affected the incidence of RV enteritis complicated with myocardial damage. Multiple factors analysis results showed that the risk factors of RV enteritis complicated with myocardial damage included in dehydration (OR=4.291), acidosis (OR=2.285) and electrolyte disturbance (OR=5.290), but age (OR=0.521) was the protective factors of RV enteritis without myocardial damage of children. Conclusion The high risk factors of RV enteritis complicated with myocardial damage of children included in age less than 1 year old, midrange and severe dehydration, acidosis, electrolyte disturbance and electrocardiographic abnormality. To aim directly at these risk factors, we should detect myocardial zymogram for making a definite diagnosis in time, and then carry out protecting heart treatment as soon as possible after definite diagnosis.
[1] 杨雯,王书孝.轮状病毒腹泻致心肌损害的各指标相关性研究[J].临床儿科杂志,2012,30(10):927-934. [2] 沈晓明,桂永浩.临床儿科学[M].2版.北京:人民卫生出版社,2013:469. [3] 冉建瑜.小儿轮状病毒肠炎致心肌损害临床分析[J].吉林医学,2012,33(4):732-733. [4] 李秀云,张晴.轮状病毒肠炎并心肌损害102例临床分析[J].中国当代医药,2012,19(21):27-28. [5] 莫台花.儿童轮状病毒肠炎合并心肌损害的临床分析[J].中国现代药物应用,2012,6(1):26-27. [6] Mark M, Rahman M, Heglen E, et al. Rotavirus incidence and genotype distribution before and after national rotavirus vaccine introduction in Belgium[J]. Vaccine, 2010,28(47):7507-7513. [7] 周文英.轮状病毒肠炎合并心肌损害的调查分析[J].中外医学研究,2014,12(9):119-120. [8] 蒋治勤,苗进.小儿轮状病毒肠炎合并心肌损害临床分析[J].陕西医学杂志,2010,39(3):364-365.
