Abstract:Objective Through the analysis of the results of ultrasound prenatal diagnosis in our hospital, to understand the relationship between the incidence, the type, the development trend of the year, time to pregnancy,gestational age and the incidence of fetal malformations. Methods General conditions and test results of pregnant women from 2009 to 2012 were registered individually, to conduct a comprehensive summary of the statistical analysis. Results There are 290 fetal malformations in 8 452 women who took the ultrasonic testing with a total incidence of 3.43%. Among the 290 malformations, the top three are 98 circulatory system malformations with an incidence of 1.16%, 55 central nervous system malformations with an incidence of 0.65% and 43 urinary system malformations with an incidence of 0.51%.The incidence of malformations in different years are changing. Time to pregnancy is related to the malformations. The incidence of malformations is higher if a woman gets pregnant in winter or spring and lower in summer and autumn. The age of the pregnant women is also related to malformations. The older the woman is, the higher the incidence will be. Conclusion Ultrasonography has an extremely important value in prenatal diagnosis. the vast majority of fetal malformation from anatomical structure can be screened out by Ultrasound. Ultrasonography is a very powerful measure to reduce the incidence of birth defects and improve the quality of the population. Health education perinatal care and prenatal and postnatal care should be carried out widely.