童年创伤与HIV感染者/AIDS患者焦虑抑郁及自杀倾向相关性研究

doi:10.3969/j.issn.1006-5253.2023.04.007.

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摘要目的探讨HIV感染者/AIDS患者(PLWHA)的儿童期创伤经历与焦虑、抑郁及自杀风险间关系，为早期识别PLWHA心理问题风险与干预提供循证证据支持与流行病学依据。方法选取于西安市某医院艾滋病专科门诊接受治疗的患者为研究对象，采用广泛性焦虑症量表(GAD-7) 评估患者焦虑水平，抑郁自评量表(PHQ9 )评定患者抑郁情绪，简明国际神经精神访谈自杀问卷部分(MINI)评估自杀风险，童年创伤问卷(CTQ)评估儿童期创伤；以频数和构成比描述定性资料，采用卡方检验进行各组间比较，通过优势比(OR)及其95%置信区间（ＣＩ）表示关联强度。结果在470例患者中，64.7%的PLWHA有过童年创伤经历，其中童年受情感虐待、躯体虐待的发生率均高于无焦虑症状者（P＜0.05）。54.5%的PLWHA患有抑郁症状。童年受到情感虐待、躯体虐待者具有自杀倾向的风险分别是未受到的4.792倍(OR=4.792, 95%CI:1.896~12.110)、3.130倍(OR=3.130, 95%CI:1.430~6.851)。结论儿童期创伤经历的PLWHA更容易发展为焦虑抑郁，并增加自杀风险。应特别关注PLWHA的心理健康状况，尤其是有童年期情感虐待与躯体虐待经历者，尽早设计相应心理干预措施，预防自杀和其他不良事件的发生。

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	靳娟
	杨佩莹
	李学敏
	高津菁
	罗培培
	张媛
	尹金玲
	米白冰
	张艳

关键词 ： HIV感染者/AIDS患者, 童年创伤, 焦虑障碍, 抑郁症, 自杀倾向

Abstract：Objective To explore the relationship between childhood trauma experience and anxiety, depression and suicide risk in HIV/AIDS patients, and to provide evidence support and epidemiological basis for early identification and intervention of psychological problems of people living with HIV/AIDS (PLWHA).Methods Participants were recruited at an AIDS outpatient department. The generalized anxiety disorder scale-7 items (GAD-7) was used to assess patients′ anxiety levels; patient health questionnaire-9 items (PHQ-9) was used to assess patients′ depression; the brief international neuropsychiatric interview suicide questionnaire section was used to assess suicide risk; and the childhood trauma questionnaire was used to assess childhood trauma. Count data were described with frequency and composition ratios, and comparisons between groups were made using chi-square tests, and the strength of association was expressed by OR and its 95% confidence interval(CI).Results Among the 470 patients investigated, 64.7% of PLWHA had traumatic childhood experiences, and the prevalence of childhood emotional and physical abuse was higher than that of patients without anxiety symptoms (P<0.05); 54.5% of PLWHA suffered from depressive symptoms. Those who were emotionally and physically abused in childhood had 4.8 times (OR=4.792, 95% CI:1.896-12.110) and 3.1 times (OR=3.130, 95% CI:1.430-6.851) the risk of suicidal ideation than those who were not, respectively.Conclusion PLWHA with childhood traumatic experiences are more likely to develop anxiety depression and increase the risk of suicide. Special attention should be paid to the mental health status of PLWHA, especially those who have experienced childhood emotional and physical abuse, and appropriate psychological interventions should be designed as early as possible to prevent suicide and other adverse events.

Key words： people living with HIV/AIDS childhood trauma anxiety depression suicidal tendency

收稿日期: 2023-04-24

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通讯作者: 米白冰，Email：xjtu.mi@xjtu.edu.cn

引用本文:

靳娟，杨佩莹，李学敏，高津菁，罗培培，张媛，尹金玲，米白冰，张艳 . 童年创伤与HIV感染者/AIDS患者焦虑抑郁及自杀倾向相关性研究[J]. 中国医院统计, 2023, 30(4): 275-280.
Jin Juan，Yang Peiying，Li Xuemin，Gao Jinjing，Luo Peipei，Zhang Yuan，Yin Jinling，Mi Baibing，Zhang Yan. Association of childhood trauma with anxiety, depression and suicidal tendency in people living with HIV/AIDS. journal1, 2023, 30(4): 275-280.

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