Abstract：Objecive To introduce the method of using empirical likelihood method to estimate the relevant parameters of accuracy evaluation of diagnostic test without a gold standard under conditional correlation hypothesis. Methods Based on the existing Hui-Walter model, the conditional simplified model is constructed, that is, under the conditional correlation hypothesis, the estimation of the relevant parameters of the diagnostic test evaluation is obtained by constructing the conditional likelihood function. Results By constructing the conditional likelihood function under the conditional correlation hypothesis, the method obtains reliable and robust estimates of related parameters, including the prevalence rate, sensitivity and specificity of the current sample.Conclusion This method simplifies the conditions for the analysis of the diagnostic test without a gold standard, expands the application range of evaluation of diagnostic test without a gold standard, and is a new and effective method to evaluate the accuracy of diagnostic test without a gold standard.
赵芃，吴立晨，闫淼佳，米白冰，陈方尧，颜虹. 条件相关假设下条件似然方法在无“金标准”诊断试验准确性评价中的应用[J]. 中国医院统计, 2021, 28(3): 206-210.
Zhao Peng, Wu Lichen, Yan Miaojia, Mi Baibing, Chen Fangyao, Yan Hong. Application of conditional likelihood method in the evaluating of diagnostic test without a gold standard under conditional correlation assumption. journal1, 2021, 28(3): 206-210.
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