Abstract：Objective To analyze the characteristics, influencing factors and potential risks of adverse drug reactions (ADR) in a tertiary psychiatric hospital, so as to provide reference for clinical prevention and disposal of adverse drug reactions of psychotropic drugs.Methods A retrospective analysis was conducted on 265 ADR case reports due to the use of psychotropic drugs reported by a psychiatric hospital from October 2019 to October 2021.Results Among the 265 reported cases with ADR, 88 were males and 177 were females, with a higher incidence among females. The average age of the patients was (42.23±17.54) years old, with the majority being young and middle-aged. Forty drugs were involved in ADRs reports, of which the number of adverse reaction reports of antipsychotics was the largest, accounting for 66.42%, followed by antidepressants, accounting for 20.38%. The top three drugs in the cumulative number of reported ADR cases were Olanzapine, Quetiapine and Risperidone respectively. The system most affected by ADRs was the digestive system, with 105 cases reported, accounting for 37.23%, followed by the nervous system, with 88 cases reported, accounting for 31.21%.Conclusion The forms of adverse reactions caused by psychiatric drugs are various, and it is difficult to identify them. Clinicians should strengthen the monitoring of the use of psychiatric drugs and use the psychiatric drugs reasonably to ensure the medication safety.
邬徐琪，孙婷. 某三甲精神病专科医院265例精神类药物不良反应回顾性分析[J]. 中国医院统计, 2022, 29(4): 270-274.
Wu Xuqi, Sun Ting. Retrospective analysis of 265 cases with adverse reactions to psychotropic drugs in a tertiary psychiatric hospital. journal1, 2022, 29(4): 270-274.
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