Abstract:Objecive To analyze the relationship between serum γglutamyltransferase (GGT) levels and metabolic syndrome in the elderly population. Methods Totally 1 249 elderly people were selected who received physical examination in Hangzhou Wuyunshan Hospital from January 2017 to December 2019, and the relationship was analyzed between serum GGT and metabolic syndrome component and the risk of having metabolic syndrome. Results The serum GGT level was positively correlated with systolic blood pressure, diastolic blood pressure, fasting blood glucose and fasting triglyceride (P<0.05), and negatively correlated with high density lipoprotein cholesterol (P<0.05). Logistic regression analysis showed that the risks of metabolic syndrome in male serum GGT 21.50-28.35 U/L group, 28.36-39.50 U/L group and >39.50 U/L group were higher than those in <21.50 U/L group (OR=1.609, 3.120, 5.601, 95%CI: 1.028-2.516, 2.016-4.820, 3.562-8.789), and the risks of metabolic syndrome in female serum GGT 15.1019.37 U/L group, 19.38-26.95 U/L group, and>26.95 U/L group were higher than those in <15.10 U/L group (OR=1.844, 2.678, 3.769, 95%CI: 1.004-3.375, 1.481-4.825, 2.102-6.740). Conclusion Increased serum GGT level in the elderly is a risk factor for the onset of metabolic syndrome, and its increase in the normal range has been closely associated with the onset of metabolic syndrome.