潍坊市寒亭区结直肠癌发病情况及影响因素研究

doi:10.3969/j.issn.1006-5253.2020.04.015

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摘要目的探索山东省潍坊市寒亭区结直肠癌发病情况及影响因素，了解寒亭区结直肠癌流行现状，为结直肠癌的预防和高危人群的筛查提供依据。方法统计寒亭区2016—2018年确诊为原发性结直肠癌的新发病例，进行发病趋势分析；采用1∶2匹配的病例对照研究方法，调查105例结直肠癌患者、210名正常对照，探索结直肠癌发病的影响因素。结果 2018年寒亭区结直肠癌发病率为28.15/10万，且40岁以上发病率逐渐增高。条件logistic回归分析结果显示，有肿瘤家族史、三餐不规律、食用腌制食品、食用肥肉是发生结直肠癌的危险因素（P＜0.05，OR>1），而睡眠质量是结直肠癌的保护因素。结论 2016—2018年寒亭区结直肠癌发病率高于全国，呈逐年上升趋势，且存在年龄差异。加强对该地区高危人群的早期干预，对降低结直肠癌的发病率和病死率具有重要意义。

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	马金金
	丰义宽
	张玉英
	姜冰
	伊文静
	丁艳乐

关键词 ：结直肠癌, 发病率, 影响因素, 潍坊市寒亭区

Abstract：Objective To explore the incidence and influencing factors of colorectal cancer and to understand the prevalence of colorectal cancer in Hantang District, Weifang City, Shandong Province, so as to provide evidence for the prevention of colorectal cancer and screening of high-risk population. Methods The newly diagnosed cases of primary colorectal cancer in Hanting District from 2016 to 2018 were collected and the incidence trend was analyzed. A 1∶2 matched casecontrol study was conducted to investigate 105 colorectal cancer patients and 210 normal controls to explore the influencing factors of colorectal cancer. Results In 2018, the incidence of colorectal cancer in Hanting District was 28.15/100 000, and the incidence of colorectal cancer in people over 40 years of age increased gradually. And multivariate logistic regression analysis showed that family history of tumors,irregular meals, pickled food and fat meat were risk factors for colorectal cancer (P＜0.05, OR>1), while sleep quality was protective factors for colorectal cancer. Conclusion From 2016 to 2018, the incidence of colorectal cancer in Hanting District is higher than that in China showing an increasing trend year by year and there was age differences. Therefore, strengthening the early intervention of highrisk population in this area is of great significance to reduce the incidence and mortality of colorectal cancer.

Key words： colorectal cancer incidence influencing factor Hanting District of Weifang

收稿日期: 2019-12-26

通讯作者: 丰义宽，Email：Fyk8192115@163.com

引用本文:

马金金，丰义宽，张玉英，姜冰，伊文静，丁艳乐. 潍坊市寒亭区结直肠癌发病情况及影响因素研究[J]. 中国医院统计, 2020, 27(4): 349-353.
Ma Jinjin, Feng Yikuan, Zhang Yuying,Jiang Bing,Yi Wenjing,Ding Yanle.. Study on the incidence and the influencing factors of colorectal cancer in Hanting District of Weifang. journal1, 2020, 27(4): 349-353.

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