Abstract：Objective To explore the characteristics and correlated risk factors of drug resistance of pulmonary tuberculosis in midde-aged and old patients. Methods Totally 645 middle aged and old patients with pulmonary tuberculosis were carried out a retrospective survey, and these patients were divided into the drug resistance group and the sensitive group according to the result of drug sensitivity test. The differences of different factors were compared between the two groups, and the risk factors of drug resistance of pulmonary tubereulosis were screened by multiple factors logistic regression method. Results The incidence rate of pulmonary tuberculosis in middle aged and old patients was 21.24% (137/645)，and mainly in multidrug resistance(61.31%). Multiple factor result showed that the risk factors of drug resistance of pulmonary tubereulosis mainly included floating population (OR=2.824)，complicated with underlying diseases(OR-3.473)，retreatment (OR-4.108), merged cavity (OR=4.522), bad treatment compliance (OR=2.550) and unreasonable drug use(OR=5.317). Conclusion Middle-aged and elderly patients with pulmonary tubereulosis have a high incidence rate of drug resistance, and mainly in multidrug resistance. The above risk factors should be considered,and the preventive measures should be adopted,to cut down the incidence rate of drug resistance of pulmonary tuberculosis.
毛晓燕，程慕蓉，徐月欢. 中老年肺结核患者耐药性特点及其相关危险因素调查[J]. 中国医院统计, 2020, 27(3): 265-267,271.
Mao Xiaoyan,Cheng Murong,Xu Yuehuan.. Investigation analysis on characteristics and correlated risk factors of drug resistance of pulmonary tuberculosis in middle aged and old patients . journal1, 2020, 27(3): 265-267,271.
