复发性脑梗死危险因素的<span>logistic回归分析</span>

doi:10.3969/j.issn.1006-5253.2019.06.007

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摘要目的探究复发性脑梗死的危险因素，旨在为临床预防及治疗提供一定参考价值。方法选取某院神经内科收治的138例脑梗死患者作为研究对象。其中，65例复发性脑梗死患者列入复发组，73例初发性脑梗死患者列入初发组。分别采用χ2检验和二元logistic回归法，分析一般临床资料与病理学因素与复发性脑梗死的关系，并探究复发性脑梗死的危险因素。结果复发组与初发组患者的糖尿病史、心房纤颤病史、短暂性脑缺血发作史及高同型半胱氨酸血症差异比较均有统计学意义（P<0.05）；而两组的脑血管病变、TOAST分型、高血压史、高脂血症史、冠心病史、嗜酒史及嗜烟史的差异比较均无统计学意义（P>0.05）。有高同型半胱氨酸血症（OR: 3.894，95% CI:1.514～10.018）、有心房纤颤病史（OR: 3.112，95% CI:1.248～7.757）、有短暂性脑缺血发作史（OR: 2.824，95% CI:1.361～5.857）和有糖尿病史（OR: 2.571，95% CI:1.293～ 5.112）是影响复发性脑梗死的危险因素（P<0.05）。结论直视复发性脑梗死的危险因素的防治可以有效降低复发性脑梗死的发生。

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	王志
	徐汉文
	杨建邦

关键词 ：复发性脑梗死, 高同型半胱氨酸血症, 短暂性脑缺血发作史, 脑血管狭窄

Abstract：Objective To explore the risk factors of recurrent cerebral infarction and in order to provide a certain reference value for clinical prevention and treatment. Methods Totally 138 patients with recurrent cerebral infarction in the Department of Neurology were selected as research objects. Sixtyfive cases with recurrent cerebral infarction belonged to the recurrence group, and 73 cases with primary cerebral infarction belonged to the primary group. The chisquare test and logistic analysis were used to analyze the relations between general clinical data and physiological factors and recurrent cerebral infarction, in order to identify risk factors of recurrent cerebral infarction. Results There were statistically significant differences between the recurrent group and the primary group in the history of diabetes, atrial fibrillation, transient ischemic attack and hyperhomocysteinemia (P<0.05). However, There were no statistically significant differences between the two groups in cerebrovascular disease, TOAST type, history of hypertension, history of hyperlipidemia, history of coronary heart disease, history of alcohol abuse and history of smoking (P>0.05). Having hyperhomocysteine (OR: 3.894, 95% CI: 1.514～10.018), history of atrial fibrillation (OR: 3.112, 95% CI: 1.248～7.757), history of transient ischemic attack (OR: 2.824, 95% CI: 1.361～5.857), and history of diabetes (OR: 2.571, 95% CI: 1.293～ 5.112) were risk factors for recurrent cerebral infarction (P<0.05). Conclusion The risk factors of recurrent cerebral infarction indicate that paying attention to these risk factors can effectively reduce the occurrence of recurrent cerebral infarction.

Key words： recurrent cerebral infarction hyperhomocysteinemia history of transient ischemic attack cerebral vascular stenosis

收稿日期: 2019-09-29

通讯作者: 杨建邦，Email：15958996782@163.com

引用本文:

王志,徐汉文,杨建邦. 复发性脑梗死危险因素的logistic回归分析[J]. 中国医院统计, 2019, 26(6): 422-424.
Wang Zhi, Xu Hanwen, Yang Jianbang. Risk factors of recurrent cerebral infarction using logistic regression analysis. journal1, 2019, 26(6): 422-424.

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［1］WANG J, YU XD, LI GQ. Comparative study on shortterm and longterm prognostic determinants in patients with acute cerebral infarction［J］. Int J Clin Exp Med, 2015, 8(6): 9855-9861.

［2］WANG J, NING R, WANG Y. Plasma Ddimer level, the promising prognostic biomarker for the acute cerebral infarction patients［J］. J Stroke Cerebrovasc Dis,2016, 25(8): 2011-2015.

［3］冯泉. 复发性脑梗死的相关危险因素分析［J］. 中国实用神经疾病杂志, 2014, 17(11): 77-79.

［4］王娟. 复发性脑梗死相关因素研究［J］. 中国全科医学, 2013, 16(3): 246-248.

［5］王锋, 李薇薇, 石学敏, 等. 首次脑梗死与复发性脑梗死危险因素分析［J］. 中华中医药杂志, 2016, 31(1): 232-234.

［6］中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组. 中国急性缺血性脑卒中诊治指南2010［J］. 中国全科医学, 2011, 14(35): 4013-4017.

［7］ADAMS HP JR, BENDIXEN BH, KAPPELLE LJ, et al. Classification of subtype of subtype of acute　ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of org 10172 in　acute stroke treatment［J］. Stroke, 1993, 24: 35-41.

［8］徐雄鹰, 周蓉靖, 白春峰, 等. H型高血压合并急性脑梗死患者血浆同型半胱氨酸水平与颈动脉内膜中层厚度的关系［J］. 中华高血压杂志, 2015, 23(4): 383-386.

［9］朱荣志, 周英, 李其英, 等. 老年脑梗死患者颈动脉粥样硬化的特征及血浆同型半胱氨酸水平的临床观察［J］. 安徽医药, 2015, 19(10): 1955-1956.

［10］尚芙蓉, 王淑媛. 血浆同型半胱氨酸与青年脑梗死的关系研究［J］. 中华全科医学, 2012, 10(3): 393, 428.

［11］许航, 冯敏, 寿广丽. 短暂性脑缺血发作进展为脑梗死危险因素分析［J］. 中华全科医学, 2012, 10(3): 373.