Abstract：Objective To investigate the prevalence and risk factors of prenatal depression among pregnant women in different stages of pregnancy.MethodsA total of 1,280 pregnant women who came to our obstetrics outpatient clinic during June 2016 to August 2017 was enrolled in this study. The general data of pregnant women were collected and the prenatal depression was analyzed by the Edinburgh Depression Scale (EPDS). The prevalence of depression in early pregnancy, second trimester and third trimester was analyzed, and the risk factors of prenatal depression in pregnant women were explored. Results Among 1 280 pregnant women, there were 417 cases (32.58%) with prenatal depression. There was no significant difference in the prevalence of prenatal depression between first trimester, second trimester and third trimester (P>0.05). Multivariate logistic regression analysis showed no work (OR=3.842,95% CI: 2.097～7.040), disharmonious spouse relationship (OR=4.242, 95% CI 1.561～11.526), abortion history(OR=3.629，95%CI：1.094～12.043). prenatal depression history (OR=6.573, 95% CI: 2.819～15.329), and gender role expectation (OR=2.171, 95% CI:1.080～4.361) were independent risk factors for prenatal depression in pregnant women (all P<0.05).Conclusion Pregnancy women have similar possibility of prenatal depression in different pregnancy stages. No work, disharmonious spouse relationship, abortion history, history of maternity depression, and expectation of fetus gender are all risk factors of prenatal depression in pregnant women, which should be taken precaution.
徐禄禄,李雅燕,赵晓玲. 孕期产前抑郁患病率及危险因素分析[J]. 中国医院统计, 2019, 26(2): 95-97.
Xu Lulu, Li Yayan, Zhao Xiaoling. Prevalence and risk factors of prenatal depression among pregnant women in different stages of pregnancy. journal1, 2019, 26(2): 95-97.
［1］WOLFORD E, LAHTI M, TUOVINEN S, et al. Maternal depressive symptoms during and after pregnancy are associated with attentiondeficit/hyperactivity disorder symptoms in their 3-to 6-year-old children［J］. Plos One, 2017, 12(12):e0190248.
［2］MASELKO J, BATES L, BHALOTRA S, et al. Socioeconomic status indicators and common mental disorders: Evidence from a study of prenatal depression in Pakistan:［J］. SSM-Population Health, 2018（4）:1-9.
［4］CHAGARLAMUDI H, KIM J, NEWTON E. Associations of Prepregnancy Morbid Obesity and Prenatal Depression with Gestational Weight Gain［J］. Southern Medical Journal, 2018，111(1):23-29.
［6］ERTEL KA, HUANG T, RIFAS-SHIMAN SL, et al. Perinatal weight and risk of prenatal and postpartum depressive symptoms［J］. Annals of Epidemiology, 2017, 27(11):695-700.
［7］ZHOU C, IBANEZ G, MIRAMONT V, et al. Prenatal maternal depression related to allergic rhinoconjunctivitis in the first 5 years of life in children of the EDEN mother-child cohort study:［J］. Allergy & Rhinology, 2017, 8(3):e132-e138.
［9］JOHNSON KM, PALEY FM, MODEST AM, et al. An assessment of depression, psychosocial factors, and resilience among women seeking prenatal care at an urban community health center［J］. International Journal of Gynecology & Obstetrics, 2017, 47(4):621-634.
［10］LIU W, WANG H, XUE X , et al. OGTrelated mitochondrial motility is associated with sex differences and exercise effects in depression induced by prenatal exposure to glucocorticoids［J］. Journal of Affective Disorders, 2017, 226(7):203.
［12］LU Y, ZHANG J, ZHANG L, et al. Hippocampal Acetylation may Improve PrenatalStressInduced DepressionLike Behavior of Male Offspring Rats Through Regulating AMPARs Expression［J］. Neurochemical Research, 2017(5):1-9.
［13］陈HOWELL KH, MILLERGRAFF LE, SCHAEFER LM, et al. Relational resilience as a potential mediator between adverse childhood experiences and prenatal depression［J］. J Health Psychol, 2017(5):135910531772345.
