Abstract:Objective To explore the characteristics and correlated risk factors of acute coronary syndrome (ACS) patients with hospital infection. Methods Sixty-five cases of hospital infection of ACS were selected as the infection group, and 130 cases of ACS without hospital infection were randomly selected as the non-infection group. With case-control study method, the correlated risk factors were retrospectively collected, and the high risk factors were screened by single factor and multiple factor methods. Results The infection rate of ACS in hospitalization was 13.8% (65/472), with infection site mainly in respiratory system and urinary system. Gram-negative bacteria were the main pathogenic bacteria. Multiple factors analysis result indicated that the risk factors of hospital infection of ACS included age (OR=1.900), diabetes mellitus (OR=3.908), COPD (OR=4.509), Invasive operation (OR=5.155), classification of cardiac function (OR=3.019) and the use of antibacteria (OR=2.442), while early revascularization (OR=0.480) was the protective factor. Conclusion ACS patients have a high hospital infection rate during hospitalization, so it should be paid attention to by medical and nursing staff. To aim directly at these high risk factors, we should early adopt intervention measures to cut down the incidence rate of hospital infection.