Abstract：Objective To explore the risk factors of diarrhea after enteral tube feeding in patients with acute cerebral infarction, in order to provide a basis for clinical improvement of prognosis. Methods Totally 112 patients with acute cerebral infarction who underwent enteral tube feeding were selected as research objects. All patients were divided into diarrhea group (47 cases) and non-diarrhea group (65 cases) according to diarrhea or not. Single factor analysis and binary logistic analysis were used to analyze the relationship between the diarrhea and 9 factors (sex, age, hypertensive, heart disease history, diabetes, infarction location, probiotics, antibiotics and nutrition), in order to identify risk factors. Results The differences in probiotics, antibiotics and nutrition between diarrhea group and non-diarrhea group had statistically significance (P<0.05). However, the differences in sex, age, hypertensive, heart disease history, diabetes and infarction location had not statistically significance (P>0.05). The binary logistic analysis found that antibiotics (OR:7.800,95%CI:3.139~19.381) was the risk factors of diarrhea (P<0.001), while probiotics (OR:0.380,95%CI:0.162~0.895) and the hole-protein nutrient solution containing cellulose (OR:0.268,95%CI:0.110~0.653) were the protective factors of diarrhea (P<0.05). Conclusion The risk factors of diarrhea after enteral tube feeding in patients with acute cerebral infarction indicated that proper use of antibiotics, improving probiotics, and selection of nutrient solution containing cellulose can valid reduce?the incidence of diarrhea.
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