Influence factor analysis of nasal continuous positive airway pressure stability for newborn
Wang Weina1, Shen Ying2
1 Department of Neonatology, the People′s Hospital of Beilun District, Ningbo 315800, China; 2 Department of Neonatology, Binjiang District of Zhejiang University Affiliated Children's Hospital
Abstract：Objective To explore the influence factors of nasal continuous positive airway pressure (NCPAP) stability for newborn, so as to provide data evidence to promote NCPAP quality. Methods The clinical data of totally 223 cases of neonatal respiratory distress syndrome was analyzed, and all the patients were treated with NCPAP and divided into 2 groups according to pressure anomaly time: ≥3 times group and ＜3 times group. SPSS19.0 was used to analyze the influence factors and risk factors of pressure anomaly. Results There was 602 times pressure anomaly in total, and 2.7 times per child. The birth body mass (t=2.601, P=0.040), NCPAP use time (t=14.217, P<0.001), stuffy nose off (χ2=12.043, P=0.001), nasal mucosa damage (χ2=11.314, P=0.001), fetus restless (χ2=4.814, P=0.028), pipe line leakage (χ2=4.332, P=0.037), secreta block (χ2=6.789, P=0.009) and excessive condensate water (χ2=5.026, P=0.025) were all influence factors for NCPAP stability. NCPAP≥72(OR=2.159,95%CI:1.212~8.874), stuffy nose off(OR=3.283,95%CI: 1.643~6.558), nasal mucosa damage (OR=2.724,95%CI:1.506~1.930), fetus restless(OR=1.873,95%CI:1.066~3.291), secreta block (OR=2.419,95%CI:1.231~4.755)and excessive condensate water (OR=2.253, 95%CI:1.095~4.637)were also risk factors for NCPAP pressure anomaly. Conclusion Necessary precautions should be taken according to the risk factors of NCPAP pressure anomaly, and timely troubleshooting is the effective measure for improving NCPAP quality.
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