Abstract：Objective To explore the structural changes of average hospitalization expenses of cancer patients from 2014 to 2019, and to study the influencing factors of hospitalization expenses. Methods We selected the inpatients with malignant tumor in a tertiary hospital from 2014 to 2019 as the research objects and collected the information on the first page of the inpatient medical records. The inpatient expenses, diagnosis and treatment were fitted by path analysis model to study the influencing factors directly and indirectly affecting the inpatient expenses. Results From 2014 to 2019, the proportion of medicine in the hospitalization expenses of patients with malignant tumor was 36.13%, followed by medical service expenses with 21.76%, and the lowest was the cost of material 0.16%; the contribution rate of other expenses and medical service expenses was 37.44% and 34.83% respectively, and the contribution rate of nursing expenses and rehabilitation expenses was 1.07% and 0.15%. Factors directly affecting the average hospitalization expenses of patients with malignant tumor were hospitalization days, surgery, years of hospitalization, marriage, age, gender, and medical payment method. Among them, the most influential factor was surgery, with an effect coefficient of 0.798, followed by hospitalization days, with an effect coefficient of 0.629. Conclusion The proportion of medicine cost in the average hospitalization expenses of patients with malignant tumor has decreased, the contribution rate of the structural change of the operation expenses is ideal, the proportion of medical service expenses has gradually increased, and the optimization control still needs to be strengthened; the influencing factors of the average hospitalization expenses are relatively complex, in order to effectively reduce the operation expenses, we should strictly grasp the surgery indications and control the hospitalization days.
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