Abstract：Objective To understand the influencing factors of transfusion reaction, and to explore the causes, characteristics and regularity of transfusion reaction, so as to provide reference for formulating countermeasures and measures to prevent and reduce transfusion reaction.Methods Eight items including sex, age, blood type, primary disease, allergy history, blood transfusion history, medication before transfusion and blood product category were collected for statistical analysis of influencing factors of transfusion reaction.Results There were 10 921 cases of operation and transfusion, including 79 cases with transfusion reaction, with the incidence 0.72%. Binary logistic regression analysis showed that the occurrence of blood transfusion reaction was significantly correlated with the three factors of primary disease, blood transfusion history and blood product category (P<0.05). Patients with malignant tumor as the primary disease, blood transfusion history 3 times and above, plasma as the blood products (compared with red blood cells) were more prone to blood transfusion reaction.Conclusion We should strictly grasp the indications of blood transfusion, rationally avoid all factors that can cause transfusion reaction, avoid and reduce transfusion reaction, and ensure the safety of clinical transfusion.
