Abstract：Objective To explore the risk factors of nosocomial infections in patients with chronic renal failure (CRF) undergoing hemodialysis, in order to provide reference basis for reducing hospital infection rate. Methods Totally 142 hospitalized CRF patients undergoing hemodialysis were selected as research objects. Thirty-six cases were with hospital infection and belonged to the infection group, and 106 cases were not with hospital infection and belonged to the non-infection group. The common part of infection was numbered. Single factor analysis and logistic analysis were used to analyze relations of hospital infection with 9 factors (sex, age, primary disease, heart failure, length of stay, dialysis age, venous catheter, hemoglobin and blood albumin), in order to identify risk factors. Results The total of infection rate was 25.35%, including 12 cases in respiratory system (33.33%), 9 cases in urinary system (25.00%), 6 cases in vascular access (16.67%), 4 cases in digestive system (11.11%), 3 cases in cyclic system (8.33%) and 2 case in others (5.56%). The differences in age, primary disease (diabetic nephropathy, chronic glomerulonephritis, chronic pyelonephritis, obstructive nephropathy, gouty nephropathy and others), heart failure, length of stay, dialysis age, venous catheter, hemoglobin and blood albumin between the diarrhea group and the non-diarrhea group were statistically significant (P<0.05). The logistic analysis showed that age>60 years (OR:2.746), diabetic nephropathy (OR:2.592), chronic glomerulonephritis (OR:2.527), heart failure (OR:2.578), venous catheter (OR:3.188) and the level of blood albumin<30 g/L (OR:4.744) were the risk factors of nosocomial infections in CRF patients undergoing hemodialysis (P<0.05). Conclusion The risk factors of nosocomial infections in CRF patiets undergoing hemodialysis indicated that active preventive treatment of high-risk groups, strict hemodialysis operation and the strengthening of nutritional support can effectively reduce the ratio of hospital infection.
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