Abstract:Objective To explore etiological and correlated risk factors of acute upper gastrointestinal bleeding in the elder population, then to provide basis for prevention and treatment of upper gastrointestinal bleeding. Methods Data of 190 patients possibly with upper gastrointestinal bleeding were retrospectively analyzed, and according to gastroscopy results, 190 cases were divided into hemorrhage group (n=65) and non-hemorrhage group (n=125). Then single factor and multiple factors analysis methods were used to analyze the risk factors of upper gastrointestinal bleeding. Results The incidence rate of upper gastrointestinal bleeding was 34.2% (65/190) in the elder. Multiple factors analysis results showed that the risk factors included age (OR=1.377), gastric ulcer history (OR=2.609), duodenal ulcer history (OR=3.203), acute gastric mucosa pathological changes (OR=2.560), helicobacter pylori infection (OR=3.511), and taking NSAIDs (OR=4.384) and ASA (OR=5.568) drugs. Conclusion The independent risk factors of acute upper gastrointestinal bleeding in the elderly population contain age, duodenal ulcer disease, helicobacter pylori infection and taking NSAIDs and ASA drugs. We should adopt protective measures for these high risk factors.
[1] 张丽娜,马治国,杨少奇,等.消化性溃疡出血死亡危险因素分析[J].中华消化杂志,2014,34(2):85-88. [2] 彭虹.探讨胃十二指肠溃疡患者上消化道出血的危险因素[J].成都医学院学报,2012,7(2):230-232. [3] 陈运.上消化道出血200例内镜检查与临床分析[J].白求恩军医学院学报,2011,9(3):193-194. [4] 刘小宁,秦林元,杨冬华,等.两水平logistic回归模型在高血压患病影响因素分析中的应用[J].中国卫生统计,2013,30(5):673-675. [5] 赵青山.上消化道溃疡伴出血患者危险因素分析[J].岭南急诊医学杂志,2013,18(4):275-276. [6] 覃敏珍.老年上消化道出血124例相关因素分析及临床治疗[J].中国老年学杂志,2013,33(2):442-443. [7] 孙毅鸿,邵伟,王怡,等.上消化道出血危险因素的巢式病例对照研究[J].药物流行病学杂志,2012,21(10):473-476. [8] KAVIANI MJ, PIRASTEHFAR M, AZARI A, et al. Etiology and outcome of patients with upper gastrointestinal bleeding: a study from South of Iran[J]. Saudi J Gastroenterol, 2010,16(4):253-259. [9] 向四国,仰涢霞,黄丽儿,等.消化性溃疡合并上消化道出血的相关危险因素分析[J].临床消化病杂志,2015,27(5):266-269. [10]谢巧玉,林霖.上消化道非静脉曲张性出血的危险因素分析[J].吉林医学,2013,34(6):1008-1009. [11]田春阳.消化性溃疡合并上消化道出血的影响因素探究[J].中国社区医师,2014,30(36):58-60. [12]李晓.消化性溃疡合并上消化道出血的影响因素分析[J]. 临床合理用药,2014,7(4):12-13.