Abstract：Objective To explore the risk factors of prognosis of acute parquat poisoning, and provide basis for preventing and treating acute parquat poisoning in clinic. Methods One hundred and eighty-three cases of acute parquat poisoning were divided into death group and survival group, and data were collected respectively by questionnaires. Then, single factor and multiple factor logistic regression methods were used to analyze correlated risk factors of prognosis. Results Multiple factors analysis results showed that age (OR=1.128), dosage of overdose (OR=1.076), blood density of parquat (OR=1.539) and SOFA score of the first day (OR=8.073) were the risk factors of death prognosis, but gastric lavage (OR=0.583), HP (OR=0.316) and HP+CVVH (OR=0.297) were the protective factors of death prognosis. The 3rd, 7th, 60th days survival rates in the HP group and HP+CVVH group were much higher than those in the control group (P<0.05). Conclusion High risk factors of acute parquat poisoning include high age, dosage of overdose, blood density of parquat, SOFA score. The early carrying out gastric lavage and blood purification techniques could obviously raise survival rate of prognosis and deserves to promote in clinic.
[1] SEOK SJ, GIL HW, JEONG DS, et al. Paraquat intoxication in sub-jects who attempt suicide:why they chose paraquat[J]. Korean J Intern Med, 2009,24(3):247-251. [2] HWANG KY, LEE E, HONG SY. Paraquat intoxication in Korea[J]. Arch Environ Health, 2002,57(2):162-166. [3] 邱泽武,张瑞萍.化学除草剂百草枯中毒[J].人民军医,2004,47(11):662-664. [4] 张琳刚,姚世红,杜运宏,等.百草枯中毒患者预后影响因素分析[J].山西医科大学学报,2014,45(6):497-499. [5] 王喆,魏芳,陈海燕,等.急性百草枯中毒患者的预后因素分析[J].天津医科大学学报,2014,20(5):392-395. [6] 赵慧,肖莉,杜妍,等.急性百草枯中毒患者预后影响因素的分析[J].中华临床医师杂志(电子版),2013,7(24):11341-11344. [7] 林涛,余华.3种不同血液净化方法治疗急性百革枯中毒疗效分析[J].中国中西医结合急救杂志,2009,16(2):116-117. [8] 宋斌,李海燕,曾燕,等.百草枯中毒的相关预后因素分析[J].现代预防医学,2013,40(8):1571-1573. [9] 范爽,李艳辉,张志博,等.序贯性血液净化治疗百草枯中毒的临床疗效评价[J].中华临床医师杂志(电子版),2013,7(1):380-382. [10]刘鹏,何跃忠,王浩春,等.急性百草枯中毒患者预后影响因素的研究[J].中华劳动卫生职业病杂志,2011,29(3):212-215.
