25 June 2018, Volume 25 Issue 3

    

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  The relationship between TSHR gene polymorphism and the prognosis of Graves′ disease in different clinical subtypes

  Zhang Ying, Liu Lin, Shen Min, Li Rujiang, Lu Hongwen

  journal1. 2018, 25(3): 161-164. https://doi.org/10.3969/j.issn.1006-5253.2018.03.001

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  Objective To investigate the relationship between thyroid stimulating hormone receptor (TSHR) gene polymorphism and the prognosis of Graves′ disease (GD) after antithyroid drugs(ATD)treatment in Weifang Han Chinese population of Shandong province. Methods A total of 1 961 patients diagnosed GD who were referred to the Endocrinology Clinic and 533 controls were included in to study from January 2010 to January 2015. By case-control study, the SNP was genotyped by Taqman probe technique on ABI QuantStudio^TM 5 real-time PCR system respectively. SPSS 24.0 was used to make statistical analysis. Results According to the study, the SNP site rs179247-A of the TSHR gene intron 1 region was demostrated significantly correlated with GD(P_Allelic＜0.001,OR=1.64,95% CI=1.42～1.89). Analysis of model of inheritance suggested that the dominant model should be preferred for rs179247(P_Dominant＜0.001). However, there was no association between the SNP site rs179247 and different clinical subtypes of GD after antithyroid drugs treatment for at least 24 months(P_Genotypic=0.553). Conclusion Our findings demonstrated that the SNP site rs179247 of the TSHR gene intron 1 region was associated with GD, rs179247-A was an independent pathogenic site.However,there was no association between the SNP site rs179247 and different clinical subtypes of GD.
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  Survey on influence factors of job satisfaction of radiologist

  Meng Weijing, Long Jinfeng, Liu Jingang, Sun Yequan, Dong Peng

  journal1. 2018, 25(3): 165-167. https://doi.org/10.3969/j.issn.1006-5253.2018.03.002

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  Objective To study the influence factors of the radiologist′s job satisfaction, and offer the proposals. Methods Questionnaire was designed to carry out the survey on radiologists in 18 public hospitals about job satisfaction in Shandong province. The data were collected and statistical analysis was performed. Results There were differences in different gender and length of service(P＜0.001). Recognition of the radiologic work, the level of the scientific research, professional skill, fairness of income distribution, and work environmental satisfaction were the influence factors of the radiologist’s job satisfaction. Conclusion Hospitals and departments of radiology should take effective measures to deal with the above factors to improve the radiologist′s job satisfaction.
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  Research of job satisfaction of medical staff in primary-level medical and health care institutions in Chengdu

  Zhang Baiyang, Yang Yikai, Liu Danping

  journal1. 2018, 25(3): 168-171. https://doi.org/10.3969/j.issn.1006-5253.2018.03.003

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  Objective To investigate the job satisfaction of medical staff in primary-level medical and health care institutions in Chengdu, in order to explore the influencing factors of job satisfaction, and to provide reference for improving the service level of primary-level medical and health institutions. Methods A two-stage random sampling method was used to survey 120 medical staff in 9 primary-level medical and health institutions in chengdu. The investigation team designed questionnaire to evaluate job satisfaction in five dimensions including work cognition, internal environment, work reward, organization and management, and social practice environment. Results The overall scores of job satisfaction in the medical staff were 87.7±13.5. The score of work cognition was 14.5±3.0, the score of the internal environment was 16.4±3.3, the score of the work reward was 21.2±3.7, the score of the organization and management was 17.9±3.6, the score of the social practice environment was 17.8±3.7, and the satisfaction of each dimension was low. Multilinear analysis showed that the satisfaction level was higher in the female than that in the male. With the growth of the age, the satisfaction level decreased. The job satisfaction of the uncompiled staff was lower than that of the intermediate title staff, and the job satisfaction of the contract staff was lower than that of the official staff. Conclusion The overall level of job satisfaction of medical staff in primary-level medical and health care institutions in Chengdu is not high. The government should continue to increase capital input in primary-level medical and health care institutions, and improve the working conditions of medical staffs, the organization and management, and the system of employment promotion, in order to improve job satisfaction of medical staffs, so as to guarantee the neighboring area residents to enjoy high quality medical and health service.
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  Effects of dietary and exercise intervention on exercise compliance in community residents with dyslipidemia

  Zhang Zhi, He Jianzhong

  journal1. 2018, 25(3): 172-175. https://doi.org/10.3969/j.issn.1006-5253.2018.03.004

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  Objective To evaluate the efficacy of dietary and exercise intervention on exercise compliance in community residents with dyslipidemia. Methods Ninety-one community-based residents with dyslipidemia were randomly assigned to either the experiment group (n=46) or the control group (n=45). Participants in the experiment group received diet and exercise intervention including community health lectures, journals for diet and exercises, and activities for exercise groups. The control group only received community health lectures. The participants′ body mass index (BMI), waist circumference and exercise compliance rates were recorded before the intervention, after the intervention, and 3 months and 6 months after the intervention. Results Movement compliance rates in the experiment group were significantly higher than those in the control group (P<0.05). BMI and waist circumference had a significant difference at various times before and after the intervention (P<0.01), and intervention methods and intervention time had significant interaction effects (P<0.01). Conclusion Dietary and exercise intervention can effectively improve exercise adherence in community residents with dyslipidemia.
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  Risk factor analysis of IFIS in age related cataract surgery

  Wen Jiquan, Hong Mingsheng, Chen Yidan, Cao Yongbao, Xu Jiehui

  journal1. 2018, 25(3): 176-178. https://doi.org/10.3969/j.issn.1006-5253.2018.03.005

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  Objective To explore the risk factors of intraoperative floppy-iris syndrome (IFIS), so as to provide evidence for its clinical prevention and treatment. Methods Totally 482 patients (554 eyes) with age related cataract treated in the hospital were analyzed retrospectively, in which 53 patients (56 eyes) occurred IFIS. The clinical data of all the patients were analyzed, and the risk factors of IFIS were established by single factor analysis and logistic regression analysis. Results Single factor analysis results showed that age, sex, body mass index, alpha 1 receptor antagonist medication history (including tamsulosin, dorsey azole oxazine, terazosin and alfuzosin), benzodiazepines drug medication history, and antipsychotic drug history were likely to affect the incidence of IFIS in cataract ultrasonic emulsification surgery (P<0.05), while visual acuity, intraocular pressure, duration, cataract nucleus hardness grading, complications and surgical type had no significant difference (P>0.05). Logistic regression analysis results showed that 70 years old and above (OR=2.079), alpha 1 receptor antagonist medication history, benzodiazepines drug medication history and antipsychotic drug history were risk factors of IFIS (P<0.05, OR>1.0). Conclusion This study systematically summarizs the influence factors and risk factors of IFIS of senile cataract surgery, and has a certain guiding significance for the clinical prevention and treatment of IFIS.
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  Investigation of thirst of patients in intensive care unit and its related factors

  Fang Lingyan

  journal1. 2018, 25(3): 179-182. https://doi.org/10.3969/j.issn.1006-5253.2018.03.006

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  Objective To understand the status of thirst of patients in intensive care unit and to explore its influencing factors. Methods The general data and clinical data of 116 ICU patients were collected from the relevant questionnaires, and the data were analyzed statistically. Results Totally 116 cases of ICU patients were monitored 553 times thirst, with the average score of thirst 6.34±1.68 points, and 86.26% (477/553) ICU patients were with a sense of thirst. Scores of thirst of different age, marital status, mode of mechanical ventilation, ICU admission time (h), SAPS Ⅱ score, and whether sedation analgesia were statistically significant. By comparison, those who were over 60 years old, married and with oxygen were less thirsty than other groups in their characteristics. Multiple logistic regression analysis results showed that marital status (OR:0.215~0.332), the mechanical ventilation mode (OR:2.022~2.335) and acute physiology score (OR:1.177~1.302) were the important factors that affected the sense of thirst of patients in the intensive care unit. Conclusion Most of the icu patients are thirsty. In particular, we should pay more attention to divorce/widowhood, traumatic breathing and the acute physiological score over 20 points, and timely detection and evaluation should be carried out reduce the adverse effects of thirst of patients.
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  Correlation research between long work hours and chronic insomnia and frequency of needle stick/sharp injuries

  Zhang Jianwei, Liang Jianli, Yu Jianmei, Li Qun

  journal1. 2018, 25(3): 183-185. https://doi.org/10.3969/j.issn.1006-5253.2018.03.007

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  Objective To examine whether long work hours and chronic insomnia are associated with needle stick and sharps injuries among hospital nurses. Methods Cross-sectional method was used to randomly recruit 1 600 full-time bedside nurses working in eight hospitals in Wenzhou. Multivariate logistic regression models were used to examine the effects of long work and chronic insomnia on needle stick and sharps injures. Results Totally 1 470 copies of valid questionnaires were retrieved, with the valid rate 91.88%. Showed that 70% nurses overworked and 16% nurses had symptoms of chronic insomnia. Incidence rate of sharp injuries was higher than that of needle stick injuries. Logistic regression analysis showed that needle stick injures and sharp injures from nurses who worked long time and had chronic insomnia experience were more than those from nurses worked fewer hours and did not have insomnia. Conclusion The rate of needle stick/sharp injuries is high. Long work hours and chronic insomnia increase the risk of these injuries. We suggest that hospital managers follow regulations on work hours and optimize shift schedules for nurses to decrease related injures.
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  Investigation analysis on risk factors and nursing strategies of hospital infection of urinary surgery patients

  Liu Aixiang, Wang Xin, Zheng Hong

  journal1. 2018, 25(3): 186-188. https://doi.org/10.3969/j.issn.1006-5253.2018.03.008

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  Objective To analyze the characteristics and risk factors of hospital infection of urinary surgery patients, and to provide nursing strategies for preventing hospital infection. Methods Totally 480 urinary surgery patients were retrospectively investigated, and they were divided into infection group (46 cases) and non-infection group (434 cases) according to whether or not with hospital infection. The incidence rate and distribution characteristics were analyzed, and correlated risk factors of hospital infection of urinary surgery patients were screened by single factor and multiple factors methods. Results The incidence rate of hospital infection of urinary surgery patients was 9.58% (46/480), mainly by urinary system, genital system and operative incision. Multiple factors analysis results showed that the factors of age (OR=2.364), complication of basic disease (OR=8.009), past urinary tract infection (OR=6.661), invasive procedure (OR=2.946), indwelling catheter (OR=3.010) and without antimicrobial prophylaxis (OR=3.661) were the risk factors of hospital infection of urinary surgery patients. Conclusion The incidence rate of hospital infection in urinary surgery stay in a high position without going down. We should adopt essential nursing intervention measures to aim directly at these risk factors of hospital infection, in order to cut down the rate of hospital infection of urinary surgery patients.
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  Case-control study on correlated risk factors of acute coronary syndrome patients with hospital infection

  Cheng Murong, Yuan Dongmin, Zhao Juwei

  journal1. 2018, 25(3): 189-191. https://doi.org/10.3969/j.issn.1006-5253.2018.03.009

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  Objective To explore the characteristics and correlated risk factors of acute coronary syndrome (ACS) patients with hospital infection. Methods Sixty-five cases of hospital infection of ACS were selected as the infection group, and 130 cases of ACS without hospital infection were randomly selected as the non-infection group. With case-control study method, the correlated risk factors were retrospectively collected, and the high risk factors were screened by single factor and multiple factor methods. Results The infection rate of ACS in hospitalization was 13.8% (65/472), with infection site mainly in respiratory system and urinary system. Gram-negative bacteria were the main pathogenic bacteria. Multiple factors analysis result indicated that the risk factors of hospital infection of ACS included age (OR=1.900), diabetes mellitus (OR=3.908), COPD (OR=4.509), Invasive operation (OR=5.155), classification of cardiac function (OR=3.019) and the use of antibacteria (OR=2.442), while early revascularization (OR=0.480) was the protective factor. Conclusion ACS patients have a high hospital infection rate during hospitalization, so it should be paid attention to by medical and nursing staff. To aim directly at these high risk factors, we should early adopt intervention measures to cut down the incidence rate of hospital infection.