25 December 2016, Volume 23 Issue 6

    

• Select all
  |

• Select
  Time-varying glucose factor: A new variable assessing the long-term average glucose level

  Zhao Chunhua, Ma Qinghua, Sun Hongpeng

  journal1. 2016, 23(6): 401-402. https://doi.org/10.3969/j.issn.1006-5253.2016.06.001

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To create a new variable (time-varying glucose factor) to assess the long-term average glucose level through integrating multiple measuring data which contain the blood glucose and hemoglobin AlC. Methods Bayesian hierarchical latent variable model could make full use of the correlation between indicators. With the relative variation of each variable considered when generating aggregative indicator, in virtue of the information between individuals, it would give a stable estimation for individuals with fewer data. Results We estimated the time-varying glucose factor using the simulation data. The correlation coefficient between factor and average blood sugar was higher than the index between long-term blood sugar and average blood sugar (0.92 VS 0.58). Conclusion We successfully built a time-varying glucose factor with the blood glucose and hemoglobin AlC. And it could reflect the long-term blood sugar level well.
     
• Select
  Investigation of prevention action and influencing factors of respiratory diseases among college students of Shandong Province

  Zhang Zhongwen, Shi Dewen, Dong Xiufen, Xuan Haiyan, Zhang Feng, Zhong Shaoxin

  journal1. 2016, 23(6): 406-408. https://doi.org/10.3969/j.issn.1006-5253.2016.06.003

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To study the prevention action of respiratory diseases in college students, to explore the influencing factors, and to provide reasonable scientific basis for the development of health education policy. Methods Using field investigation, we conducted a questionnaire survey among students from Shandong University, Shandong Institute of Business and Technology, Binzhou Medical College, Taishan Medical College in order to analyze prevention action score of respiratory system disease and explore its influencing factors. Results Compared with non-medical students, medical students smoked less, and the difference had statistic significance(Z=-2.630, P<0.05). The constituent ratio of medical students of using computers and TV was smaller than that of non-medical students, and the difference had statistic significance (Z=-2.923, P<0.05). But the frequency of taking part in physical exercise of medical students was smaller than that of non-medical students, and the difference had statistic significance (Z=-2.961, P<0.05). Medical students who used health products or nutritional supplements were less than non-medical students (χ²=9.908, P<0.05), and a lot of students stayed up too late no matter what their majors were. Through stepwise regression analysis, prevention action score of girl students, students majored in non-medical and students having immediate family members work in medical institutions was higher, and the difference had statistic significance. Conclusion Respiratory system disease cognitive status of medical students is better than that of ordinary students, but perhaps due to more courses and pressure, their action performance is insufficient, so the school still need to strengthen health education of the respiratory system disease for ordinary students through various channels.
     
• Select
  Investigation analysis on correlated risk factors of hyperbilirubinemia of neonate patients

  Dai jin, Luo Qunyan, Jia Lina

  journal1. 2016, 23(6): 409-411. https://doi.org/10.3969/j.issn.1006-5253.2016.06.004

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To explore correlated risk factors of hyperbilirubinemia of neonate patients, and provide basis for preventing hyperbilirubinemia of neonate. Methods One hundred and eighty neonates with hyperbilirubinemia were classified as case group, and 180 healthy neonates were classified as control group. With Case-control study method, single factor was respectively compared between the two groups, and the risk factors of hyperbilirubinemia of neonates were screened by multiple factors logistic regression method. Results Multiple factors logistic regression analysis results showed that the factors of fetal age (OR=4.019), complication of fetation (OR=4.080), fetal distress (OR=1.865), infection (OR=3.277), HIE (OR=2.689) and score of 1 min Apgar (OR=5.249) were all the risk factors of hyperbilirubinemia of neonates. Conclusion The high risk factors of hyperbilirubinemia of neonate included premature birth, complication of fetation, fetal distress, infection, HIE and low Apgar. We should think highly of antenatal examination and the detection of postpartum bilirubin, and take the necessary intervention measures for high risk factors.
     
• Select
  Non-conditional logistic regression analysis on the influencing factors of the adverse reaction of ciprofloxacin injection

  Li Jiandi, Shen Zhihua

  journal1. 2016, 23(6): 412-414. https://doi.org/10.3969/j.issn.1006-5253.2016.06.005

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To observe the adverse reaction types of ciprofloxacin injection and to explore the influencing factors on the incidence of adverse reactions. Methods The cases of ciprofloxacin injection were studied in our hospital from January 2013 to December 2015, and retrospective analysis was used to record the gender, age and other clinical data of the patients. Characteristics and incidence rate of adverse reaction of ciprofloxacin injection were statistically studied, and non-conditional logistic regression analysis was used to explore the possible factors influencing the adverse reaction of ciprofloxacin injection. Results A total of 1 689 cases were included in the study, and among them, 53 cases of adverse reactions were caused by ciprofloxacin, with the incidence rate 3.14%. The adverse reactions mainly occurred in the digestive system, nervous system and skin appendages, accounting for 90.57% of all the adverse reactions. Chi square test single factor analysis showed that age, history of allergies, the combination of medication, course of treatment and dosage of the drug may be the risk factors for adverse reaction of ciprofloxacin injection, and the results of non conditional logistic regression analysis showed that age, history of allergy, combined medication, treatment duration and dosage were independent risk factors for adverse reaction of ciprofloxacin (P< 0.05). Conclusion The incidence rate of adverse reaction of ciprofloxacin injection is low, but the adverse reaction can occur in multiple organ systems, and the incidence is high in digestive system, nervous system, skin and accessory system. Non conditional logistic regression showed that age, history of allergy, combined use of other antimicrobial agents, and drug administration were all independent risk factors for adverse reaction of ciprofloxacin injection. Clinical application of ciprofloxacin injection needs a detailed understanding of the patient′s history and related information, and patients with high-risk should pay close attention to the possible adverse reactions.
     
• Select
  Correlated risk factors analysis on prognosis of death of acute parquat poisoning patients

  Gan Huiling, Li Xiaoyan, Xu Hui

  journal1. 2016, 23(6): 415-417. https://doi.org/10.3969/j.issn.1006-5253.2016.06.006

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To explore the risk factors of prognosis of acute parquat poisoning, and provide basis for preventing and treating acute parquat poisoning in clinic. Methods One hundred and eighty-three cases of acute parquat poisoning were divided into death group and survival group, and data were collected respectively by questionnaires. Then, single factor and multiple factor logistic regression methods were used to analyze correlated risk factors of prognosis. Results Multiple factors analysis results showed that age (OR=1.128), dosage of overdose (OR=1.076), blood density of parquat (OR=1.539) and SOFA score of the first day (OR=8.073) were the risk factors of death prognosis, but gastric lavage (OR=0.583), HP (OR=0.316) and HP+CVVH (OR=0.297) were the protective factors of death prognosis. The 3^rd, 7^th, 60^th days survival rates in the HP group and HP+CVVH group were much higher than those in the control group (P<0.05). Conclusion High risk factors of acute parquat poisoning include high age, dosage of overdose, blood density of parquat, SOFA score. The early carrying out gastric lavage and blood purification techniques could obviously raise survival rate of prognosis and deserves to promote in clinic.
     
• Select
  Influencing factor analysis of prognosis of acute ischemic stroke patients

  Hou Yuehui, Lin Li, Yang Jianwei, Liang Xiaoyu, Wang Xin

  journal1. 2016, 23(6): 421-423. https://doi.org/10.3969/j.issn.1006-5253.2016.06.008

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To explore the high risk factors of prognosis death of acute ischemic stroke population, and evaluate the effects of these high risk factors screening of acute ischemic stroke. Methods Two hundred and twelve patients with cute ischemic stroke were divided into survival group and death group according to whether death or not after one-year discharge from the hospital. Single factor was compared between both groups. With multiple factors method we screened independent risk factors, and analyzed diagnostic effects with BNP and NIHSS score screening prognosis of acute ischemic stroke. Results The death rate of prognosis of acute ischemic stroke in the duration of hospital stay was 15.09% (32/212). Multiple risk factors analysis result showed that atrial fibrillation (OR=3.819), cerebral infarction of a large area (OR=6.228), BNP of blood plasma (OR=5.191) and NIHSS score (OR=3.536) were the independent risk factors of prognosis death of acute ischemic stroke. The sensitivity, specificity and accuracy of NIHSS score screening prognosis were respectively 90.6%, 75.0% and 77.4%, and those of BNP were respectively 84.4%, 81.7% and 82.1%. Conclusion These factors of atrial fibrillation, cerebral infarction of a large area, BNP of blood plasma and NIHSS score are the independent risk factors of prognosis death of acute ischemic stroke. Of the total, BNP of blood plasma and NIHSS score could be predictive indexes of prognosis death of acute ischemic stroke.
     
• Select
  Risk factors investigation analysis on rehaemorrhagia about intracranial rupture aneurysm patients before operation

  Shang Qinfen, Yang Ling, Huang Danhong

  journal1. 2016, 23(6): 424-426. https://doi.org/10.3969/j.issn.1006-5253.2016.06.009

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To explore the correlated risk factors of rehaemorrhagia about intracranial rupture aneurysm patients before operation, and provide basis for preventing rehaemorrhagia. Methods With retrospective case-control study method, 465 cases of definite intracranial rupture aneurysm patients before operation were investigated by questionnaire. These cases were divided into rehaemorrhagia group (n=113) and non-rehaemorrhagia group (n=352), and the risk factors of rehaemorrhagia were screened by single factor and multiple factors methods. Results The incidence rate of intracranial rupture aneurysm patients before operation reached up to 24.3% (113/465). Multiple factors logistic regression analysis results showed that these factors such as history of hypertension (OR=4.092), complication with cerebral angiospasm (OR=1.893), epilepsy (OR=3.013), tumor diameter (OR=2.787), and moving too early or out-of bed activity of prematurity (OR=4.179) were all the risk factors of rehaemorrhagia about intracranial rupture aneurysm patients before operation. Conclusion There is still a little high incidence rate of rehaemorrhagia about intracranial rupture aneurysm patients before operation, and it affects the prognosis of these patients. There are many risk factors affecting the incidence rate of rehaemorrhagia, so we should adopt intervention measures to aim directly at these high risk factors.
     
• Select
  Application of evidence-based nursing in improving the quality of nursing in department of neurosurgery

  Liu Shuang, Ji Dongyue, Zhu Xiujing, Chen Haili, Li Xiuzhu, Chen Su′e, Chen Lili

  journal1. 2016, 23(6): 427-429. https://doi.org/10.3969/j.issn.1006-5253.2016.06.010

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To explore the application effect of detailed management based on evidence-based nursing in improving the nursing quality during operations in the department of neurosurgery. Methods Three hundred surgical patients in our hospital were included to investigate the operation. From April 2014 to July 2015, details management based on the evidence-based nursing was implemented, and 150 patients were selected. From January 2013 to March 2014, 150 patients were selected as the control group to compare the differences in the quality of nursing before and after the implementation for analysis. Results Preoperative preparation indicators such as preparation time(10.1+1.9 minutes) for operation items after the implementation were less than those before the implementation(P<0.05). The intraoperative preparation indicators such as the accuracy(98.7%) of item preparation after the implementation were higher than those before the implementation(P<0.05). The nursing satisfaction rate of chief surgeons(98.0%) and nursing satisfaction rate of patients(97.3%) after the implementation were higher than those before the implementation (P<0.05). Conclusion The application of evidence-based nursing during operations in the department of neurosurgery can effectively improve the quality of nursing and enhance the satisfaction degree of the patients.
     
• Select
  Effectiveness evaluation of early HP combined with CVVH treating acute paraquat poisoning

  Wang Dandan, Dai Wenzhen, Liu Fang

  journal1. 2016, 23(6): 433-435. https://doi.org/10.3969/j.issn.1006-5253.2016.06.012

  Abstract ( ) Download PDF ( )   Knowledge map   Save

  Objective To explore the effect of early HP combined with CVVH treating acute paraquat poisoning (PQ). Methods One hundred and eighty-three patients with PQ were divided into control group (75 cases), HP group (65 cases) and HP+CVVH group (43 cases) according to treatment methods. The survival rates of 3^rd, 7^th and 60^th days were compared among the three groups, and their prognosis effects were analyzed. Results The survival rates of 3^rd, 7^th, 60^th days in the HP+CVVH group were respectively 86.0%, 65.1% and 46.5%, much higher than those in the control group (56.0%, 41.3%, 21.3%, all P<0.05). The survival rates of 3^rd, 7^th, 60^th days in the HP group were respectively 75.4%, 56.9% and 43.1%, much higher than those in the control group (56.0%, 41.3%, 21.3%, all P<0.05). The median survival days of HP+CVVH group and HP group were respectively 40 days and 15 days, both much higher than those the control group (3 days, P<0.01). Conclusion Blood purification techniques (HP, CVVH) could obviously raise median survival days and survival rate of prognosis. Finding out the timing of blood purification and treatment time of acute parquat poisoning could provide basis for clinical popularization.