25 February 2017, Volume 24 Issue 1

    

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  Study on the incidence and risk factor of in-stent restenosis in elderly coronary heart disease patients after percutaneous coronary intervention

  Zhang Xiaofang, He Wenjun

  journal1. 2017, 24(1): 1-4. https://doi.org/10.3969/j.issn.1006-5253.2017.01.001

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  Objective To study the incidence and risk factor of in-stent restenosis (ISR) in elderly coronary heart disease (CHD) patients after percutaneous coronary intervention (PCI), and provide basis for prevention and control of ISR. Methods Clinical data of 475 cases receiving 12-month follow-up and coronary arteriography recheck were collected. Incidence of ISR was analyzed and compared between groups. Patients were grouped according to occurrence of ISR, and correlative factor was compared between ISR group and non-ISR groups to screen variables for multi-factor Logistic analysis. Results Totally 475 CHD patients completed follow-up after PCI, with 611 stent implantation, and 51 (10.67%) patients with 71 (11.62) stents encountered ISR. ISR rate of male (12.24%) was higher than that of female (6.82%) with statistical significance (P<0.05). Single-factor analysis revealed there was difference of complication with T2DM, hsCRP level, stent diameter, stent length, and stent number between both groups (P<0.05). Multi-factor analysis revealed complication with T2DM (OR=2.467, 95%CI: 1.455~5.767), hsCRP level (OR=6.515,95%CI: 2.455~18.767), stent diameter (OR=4.120, 95%CI: 1.574~14.644), stent length (OR=1.996, 95%CI: 1.387~3.895), and stent number (OR=3.425, 95%CI: 1.812~6.774) were independent factors of ISR. Conclusion ISR incidence after PCI was still high, and complication with T2DM, high hsCRP level, short stent diameter, long stent, and a large number of stents could be risk factors of ISR after PCI.   
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  Comparative study of ARIMA model and GM (1,1) model in hospital outpatient service forecast

  Liu Guozhu

  journal1. 2017, 24(1): 5-8. https://doi.org/10.3969/j.issn.1006-5253.2017.01.002

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  Objective To evaluate the effectiveness of ARIMA and GM(1,1) models in outpatient population forecasting, and to provide the basis for selecting appropriate predictive methods. Methods ARIMA model and GM (1, 1) model were constructed using monthly data of outpatient visits from 2005 to 2014. At the same time, the number of outpatients in 2015 was forecasted, and the results of the two models were validated by the actual number of outpatients in 2015. The evaluation indexes were average relative error and mean absolute value error. Results The average error rate (MER) of ARIMA and GM(1,1) models were 3.90% and 4.41%, respectively. The coefficients of determination R² were 0.961 and 0.955, respectively. For the year 2015, the average relative errors between the predicted value and the measured value were 23 959 and 35 397, the average absolute errors were 4.62% and 6.83% respectively. Conclusion ARIMA model has a better effect than GM (1,1) model on samples over 30 and on the long-term trend, cyclical trend and implicit seasonal change trend. For the data such as the number of outpatients in time series, we should consider ARIMA Model first to get a better fitting effect, and the relative error is smaller.
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  Application of open surgery and endovascular intervention in the treatment of aortic dissection and thoracic aortic aneurysm

  Xiong Ying, Long Sizhe

  journal1. 2017, 24(1): 9-11. https://doi.org/10.3969/j.issn.1006-5253.2017.01.003

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  Objective To know the service condition of the open surgery and the intravascular endovascular interventional procedures in aortic dissection and thoracic aortic aneurysm. Methods A survey was conducted by means of the retrospective method and medical records retrieval system and all data of 447 cases were analyzed statistically. Results In ten years of surgical treatment of aortic dissection aneurysm, the proportion of open surgery accounted for 29.97% and the proportion of vascular interventional surgery accounted for 70.03%. The proportion of interventional surgery increased year by year. While in thoracic aortic aneurysm surgical treatment, the proportion of open surgery accounted for 44.44% and the proportion of vascular interventional surgery accounted for 55.56% (χ²＝6.821, P＜0.01). Interventional surgery has become the mainstream in the treatment of aortic dissection in recent years. In surgical treatment of aortic dissection, the cure rate of interventional surgery was 96%, and the cure rate of open surgery was improved by 71.03% (χ²＝45.96, P＜0.01). The cure rate of interventional surgery was significantly different from open surgery. While there was no difference in the rate of cure and improvement between interventional surgery and open surgery in treatment of thoracic aortic aneurysm (χ²＝0.125,P＞0.05). Conclusion The intravascular endovascular interventional procedures decrease the average length of stay and postoperation or preoperation length of stay, average hospitalization expenses and average drug expenses. And it increases the cure and improvement rate in aortic dissecting aneurysm.   
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  Simulation of real SNPs data and evaluation on the results

  Liu Yunliang, Xiao Chun, Shi Xiaowen, Liu Yan

  journal1. 2017, 24(1): 12-16. https://doi.org/10.3969/j.issn.1006-5253.2017.01.004

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  Objective To explore the effective methods of computer simulation based on real SNPs, and to explore the relationship between SNPs and diseases, in order to provide some help for gene-gene interaction research. Methods The real SNPs data were simulated by gs2.0 software, and the simulation results were evaluated by Haploview, Plink and MDR software. Results The 500, 1000, 5000 SNPs of chromosome 22 of the Dai population in China were used as the original data to generate the simulation data of single pathogenic site and two interacting pathogenic sites respectively by use of gs2.0 software. The results showed that the original data was similar to the LD model of the simulation data, and there were close r² values. The difference of the single pathogenicity was significant, and the two interacting pathogens could be identified by MDR. Conclusion Gs2.0 is a simple and efficient computer simulation software, which can simulate the LD mode of SNPs and can set single pathogenic sites and two interaction sites to generate SNPs simulation data in batches.   
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  Analysis on equity of Beijing′s health resource allocation based on Gini coefficient and index of dissimilarity

  Bai Ling

  journal1. 2017, 24(1): 17-20. https://doi.org/10.3969/j.issn.1006-5253.2017.01.005

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  Objective To acquire the current equity situation and development trend of health resource allocation in Beijing so as to provide reference evidence for implementing regional health plan and optimizing health resource allocation. Methods The equity of health resource allocation in population and geography of Beijing in 2005 was assessed by Gini coefficient, HRDI and index of dissimilarity. Results The Gini coefficients for different kinds of health resource ranged from 0.060 to 0.120 in population, from 0.650 to 0.730 in geography and from 0.230 to 0.310 by HRDI. Both Gini coefficient and index dissimilarity of nurses were the highest in population and geography. Gini coefficient and index of dissimilarity in geography allocation of health resources were higher than those in population allocation. Besides, the equity of the hospital bed configuration was better than that of health human resources. Conclusion In 2015, the material resource allocation in health was better than human resource allocation while the nurse allocation equity was poor in Beijing. The population allocation of health resources in health was better than the geography allocation. There were significant gaps among regions. To promote the equity of health resource allocation, it was recommended to increase health investment, strengthen the guidance effect of health policy, optimize the geographic allocation and internal structure of health human resources.   
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  Analysis on the neonatal disease composition and death causes in hospital from 2006 to 2015

  Liu Yanhong

  journal1. 2017, 24(1): 21-23. https://doi.org/10.3969/j.issn.1006-5253.2017.01.006

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  Objective To understand the disease composition and neonatal death causes, and to provide a scientific basis for guiding neonatal disease control and prevention, reducing the fatality rate, and improving the quality of life. Methods Totally 17 158 cases born within 28 days from the year 2006 to 2015, were selected and Excel XP was used to analyze the indexes such as gender, age, patient disease constitution and death causes etc. Results The morbidity varied from genders, and the ratio was 1.75∶1. the proportion of newborns under 7days was the highest, accounting for about 76.65%. Among the neonatal diseases, the top three were premature infants, neonatal pneumonia, and neonatal hyperbilirubinemia. Premature birth was the main cause of death. Conclusion We should strengthen the management of perinatal pregnant women, and prevent and treat intrauterine infection diseases actively. Early diagnosis and treatment should be carried out for the illness of newborns, to improve the life quality of newborn babies.   
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  Using efficiency index model and scatter diagram to evaluate beds efficiency

  Niu Wenyan

  journal1. 2017, 24(1): 24-26. https://doi.org/10.3969/j.issn.1006-5253.2017.01.007

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  Objective To explore the evaluation method of bed utilization, and to provide support for the decision-making of hospital administrators. Methods Bed utilization rate and bed turnover times were combined and processed through mathematical methods to get bed efficiency index, and the scatter diagram got through Excel was divided into four quadrants to evaluate ward bed utilization efficiency. Results The efficiency index model showed that of the forty-three units, the efficiency index of twenty-one units was above 1, the efficiency index of twenty-two units was below 1, and the highest efficiency index was 2.24. The scatter plot showed that in sixteen wards, the bed utilization rate was above 93%, and the bed turnover times were above 38.3; in seven wards, the bed utilization rate was above 93%, the bed turnover times were below 38.3; in fourteen wards, the bed utilization rate was below 93%, and the bed turnover times were below 38.3; and in four wards, the bed utilization rate was below 93%, and the bed turnover times were above 38.3. Conclusion The evaluation method combined efficiency index model with quadrant diagram is simple and easy to evaluate the bed efficiency and regulate the configuration of the ward beds.   
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  Intervention effect evaluation on septic shock patients carrying out comprehensive intervention

  Huang Danhong, Yao Liping, Shang Qinfen

  journal1. 2017, 24(1): 27-29. https://doi.org/10.3969/j.issn.1006-5253.2017.01.008

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  Objective To explore the intervention effect of septic shock patients carrying out comprehensive intervention measures. Methods Eighy-four septic shock patients were randomly divided into control group and intervention group, respectively 42 cases. The control group was given usual care measures, while the intervention group was carried out comprehensive nursing intervention measures. The indexes of persistence time of septic shock, use length of breathing machine, incidence rate of MODS, length of stay in hospital, clinical satisfaction degree and total effective rate were compared between the two groups. Results The indexes of persistence time of septic shock, use length of breathing machine, incidence rate of MODS, length of stay in hospital of the intervention group were much less than those of the control group(P<0.05). The satisfaction rate of the intervention group was 90.5% (38/42), much higher than that of the control group (25/42(59.5%), P<0.01). The total effective rate of the intervention group was 88.1%(37/42), much better than that of the control group (66.7%(28/42), P<0.05). Conclusion The carrying out of comprehensive nursing intervention measures for septic shock patients might obviously improve patient′s condition, raise clinical curative effect and treatment satisfaction degree, and cut down length of stay in hospital.   
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  Statistical analysis of the oral antihypertensive drugs in our hospital from 2012 to 2014

  Huang Lei, Chen Shan, Wu Xuedan, He Ying

  journal1. 2017, 24(1): 30-33. https://doi.org/10.3969/j.issn.1006-5253.2017.01.009

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  Objective To study the application status of antihypertensive drugs in our hospital from 2012 to 2014, and provide evidence for clinical drug use. Methods The oral application of antihypertensive drug dosage, drug type, frequency, sales amount and defined daily cost of 2012 to 2014 in our hospital were analyzed retrospectively. Results The consumption quantity of oral antihypertensive drugs in our hospital increased year by year; calcium-channel blocker (CCB), angiotensin receptor blocker (ARB), and angiotensin converting enzyme inhibitor (ACE I) ranked top three in sale amount; CCB, diuretics, and ARB ranked top three in frequency of drug use; Amlodipine Besylate Tablets (Norvasc) and Felodipine Sustained Release Tablets (Plendil) ranked top two in sale amount for single-drug, followed by Losartan Potassium Tablets (Cozaar) in 2012, which was replaced with Irbesartan; Levamlodipine Besylate Tablets, Spironolactone Tablets and Irbesartan Tablets ranked top three in DDDs. Conclusion The utilization structure of oral antihypertensive drugs in our hospital is basically reasonable.   
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  Study on extent and correlated influencing factors of cognitive function injury of depressed elderly patients

  Zou Chenjun, Zhang Yingzhong, Liu Zhiwang, Tao Changlin

  journal1. 2017, 24(1): 34-36. https://doi.org/10.3969/j.issn.1006-5253.2017.01.010

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  Objective To explore the extent and correlated influencing factors of cognitive function injury of depressed elderly patients, provide basis for preventing cognitive function injury. Methods Totally 158 depressed elderly patients were divided into injury group (n=103) and non-injury group (n=55). With questionnaire and scales we evaluated both groups of patients, compared MMSE and ADL scores between both groups, then analyzed the influencing factors of the correlated risk factors of cognitive function injury. Results The incidence rate of cognitive function injury was 65.2% in these 158 cases of depressed elderly patients. The scores of MMSE, subjective support degree, objective support degree and support availability in the injury group were much lower than those in the non-injury group (P<0.05). But ADL score in the injury group was much higher than that in the non-injury group (P<0.05). Conclusion There was a high incidence rate of cognitive function injury in these depressed elderly patients, the mental status and activity of daily living of the patients with cognitive function injury descend in some extent. The high risk factors of cognitive function injury of depressed elderly patients include living alone, diabetes, experience many life events, and low social support.