非酒精性脂肪性肝病患者血清尿酸、血糖与冠心病的关系

doi:10.3969/j.issn.1006-5253.2020.06.005

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Abstract

Objective To analyze the relationship between serum uricemia, blood glucose and coronary heart disease in patients with nonalcoholic fatty liver disease (NAFLD). Methods Two hundred and nineteen NAFLD patients with coronary angiography admitted to our hospital from January 2016 to December 2016 were enrolled. Ultrasound or CT examination was used to diagnose fatty liver. Factors affecting coronary artery disease were analyzed by Logistic multivariate regression. Results Among all NAFLD patients, 62 were nonCHD patients and 157 were NAFLD patients with CHD. In NAFLD patients with coronary heart disease, ALT, AST, GGT, Cr, SUA and GLU increased and HDL decreased compared with NAFLD patients, and the differences were statistically significant. Multivariate Logistic regression analysis showed that increased risk of coronary heart disease was associated with blood glucose (OR=1.426, 95%CI:1.077-1.887) and serum uric acid (OR=1.005，95%CI:1.001-1.009) in males(OR=2.296, 95%CI: 1.153-4.572). Conclusion In patients with NAFLD complicated with coronary heart disease, it is necessary to timely understand the risk factors, control blood glucose level and serum uric acid level, strengthen intervention, and reduce the incidence of coronary heart disease.

Key words： nonalcoholic fatty liver disease coronary heart disease serum uric acid blood glucose

Received: 28 June 2020

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	Articles by authors
	Wang Xiaohan
	Shen Liang
	Chen Yunqing
	Shen Yueyu
	Gao Chen
	Hou Zhentao
	Han Feng
	Ji Zizhong

Cite this article:

Wang Xiaohan,Shen Liang,Chen Yunqing, et al. Relationship between serum uricemic, blood glucose and coronary heart disease in patients with nonalcoholic fatty liver disease[J]. journal1, 2020, 27(6): 494-497.

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http://manu58.magtech.com.cn/Jwk_zgyytj/EN/10.3969/j.issn.1006-5253.2020.06.005 OR http://manu58.magtech.com.cn/Jwk_zgyytj/EN/Y2020/V27/I6/494

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