|
|
|
| Study on the influencing factors of breast conserving surgery for early breast cancer based on multiple correspondence analysis |
| Li Xi, Liu Meina, Zhang Qiuju |
| Health Statistics Teaching and Research Section, Public Health College, Harbin Medical University, Harbin 150081, China |
|
|
|
|
Abstract Objective To use multiple correspondence analysis (MCA) to obtain the influencing factors of receiving breast conserving surgery (BCS) for early breast cancer patients, so as to provide data supports for improving the adherence rate of BCS. Methods We collected the case data of early breast cancer patients who underwent BCS and mastectomy. Chi square tests were used to investigate the relationship between the influencing factors and operation methods in the contingency tables; the twodimensional graph of MCA was used to show the corresponding relationship between influencing factors and breast conserving surgery, and the influencing factors were determined according to the corresponding relationship between different factors and their different classifications in the graph. Results Totally 2 423 cases with early breast cancer were collected, and the rate of breast conserving surgery was 7.88%. The results of chi square tests showed that there were 10 influencing factors with statistical significance. MCA showed that the most important factor affecting patients receiving the BCS was times of birth, followed by the age of patients, tumor histological grade and stage. Conclusion In patients with indications of breast conserving therapy, the proportion of BCS was relatively low, so we may make relevant policies to improve the breast conserving therapy according to the influencing factors obtained in this paper. It is suggested that we should improve the level of operation and communication between doctors and patients, increase the promotion of BCS, and improve the prognosis and quality of life of early breast cancer patients.
|
|
Received: 31 May 2020
|
|
|
|
［1］BRENNAN M, HOUSSAMI N. Newly diagnosed early breast cancer-an update on pre-operative assessment and staging［J］. Aust Fam Physician, 2012, 41(11):871-874.
［2］张玉铃，陈春发．某肿瘤专科医院2011—2015年1830例乳腺恶性肿瘤统计分析［J］．中国医院统计，2017，24(1)：59-60．
［3］欧阳驰斌，杜正贵．保乳治疗和乳房全切除对不同管腔亚型早期乳腺癌患者预后影响的meta分析［J］．中国普外基础与临床杂志，2020，27(3)：326-336．
［4］李翔．保乳手术和改良根治术治疗早期乳腺癌的临床疗效分析［J］．中华普外科手术学杂志(电子版)，2017，11(3)：222-225．
［5］VERONESI U, CASCINELLI N, MARIANI L, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer［J］. N Engl J Med, 2002, 347(16):1227-1232.
［6］岑况.因子分析中变量和样品空间的统一［J］.地质科技情报. 1994,13(4):93-97.
［7］党耀国，米传民，钱吴永．应用多元统计分析［M］．北京：清华大学出版社，2012．
［8］KUMMEROW K L, DU L P, PENSON D F, et al. Nationwide trends in mastectomy for early-stage breast cancer［J］. JAMA Surg, 2015, 150(1):9-16.
［9］COLLINS I M, LUM C, VERSACE V L. Influence of socioeconomic factors and distance to radiotherapy on breast-conserving surgery rates for early breast cancer in regional Australia; implications of change［J］. Asia Pac J Clin Oncol, 2018, 14(5):e224-e230.
［10］LEE M C, ROGERS K, GRIFFITH K, et al. Determinants of breast conservation rates: Reasons for mastectomy at a comprehensive cancer center［J］. Breast J, 2009, 15(1):34-40.
［11］张保宁．乳腺癌保乳手术的年龄与切缘［J］．中华普通外科学文献(电子版)，2009，3(4)：265-266．
［12］VAN MAAREN M C, DE MUNCK L, DE BOCK G H, et al. 10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: A population-based study［J］. Lancet Oncol, 2016, 17(8):1158-1170.
［13］张培，李霞，李国媛．早期乳腺癌患者影响保乳手术选择的因素分析［J］．天津护理，2013，21(6)：479-481．
［14］HOKANSON P, SESHADRI R, MILLER K D. Underutilization of breast-conserving therapy in a predominantly rural population: Need for improved surgeon and public education［J］. Clin Breast Cancer, 2000, 1(1):72-76.
［15］周建凤，郑萍，刘利停．认知行为干预对乳腺癌术后患者自我形象影响的分析［J］．中国医院统计，2017，24(5)：350-352．
|
|
|
|
