基于倾向评分法研究医院获得性肺炎对患者临床结局及医疗成本的影响

doi:10.3969/j.issn.1006-5253.2020.03.012

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Abstract Objective To estimate the impact of hospital-acquired pneumonia (HAP)on patient clinieal outcomes andmedical cost. Methods Medical records of patients discharged from Wenzhou people's hospital between May 1,2017 and June 7，2018 were reviewed. Patients were divided into two groups according to whether with hospital-acquired pneumonia. We developed a HAP propensity model and matched cases with non-HAP by propensity score at a 1:6 ratio.The differences were comparedinhospital mortality, length of stay and medical cost before and after matching. Results Among 44937patients,314 HAP cases were identified. Before matching,the in-hospital mortality rates were 3.6% (15/415) for those with HAP and 0.1%(56/44623) for those without HAP (OR=28.9,95%CI:15.0-55.7). After matching,HAP patients had higher mortality( 3.9%vs1.2%；P=0.003)，longer length of stay[(M=24,IQR=17)vs(M=8，IOR=9)days;P<0.001],and higher medical cost[(M=33450.2,IQR=31572.3)vs(M=11375.9，IQR=14230.9)；P<0.001]compared with matched non-HAP. HAP was significantly associated with in-hospital mortality (OR=3.2，95%Cl:1.5～6.8),inecreased length of stay(absolute difference =19.9, 95% Cl:17.2～22.6) and higher medical cost (absolute difference=30438.4,95%CI:26367.0～34509.7).Conclusion Patients with HAP contribute to higher in hospital mortality,longer length of stay and higher medical costs compared with non-HAP patients.

Key words： hospital acquired pneumonia hospital mortality cost and cost analysis nosocomial infection propensity score

Received: 01 October 2910

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	Chen Zhihui
	Wu Hongmei
	Wang Chenhong
	Xu Ziqin
	Gao Shengchun
	Chen Le

Cite this article:

Chen Zhihui,Wu Hongmei,Wang Chenhong, et al. Impact of non-ventilated hospital-acquired pneumonia on patient clinical outcomes and medical cost:a propensity score-matched analysis[J]. journal1, 2020, 27(3): 236-241.

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http://manu58.magtech.com.cn/Jwk_zgyytj/EN/10.3969/j.issn.1006-5253.2020.03.012 OR http://manu58.magtech.com.cn/Jwk_zgyytj/EN/Y2020/V27/I3/236

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