Objevtive To understand the incidence of postpartum depression and to analyze the influencing factors of postpartum depression, so as to provide reference for mental health care during pregnancy.Methods Totally 3 931 women 6 to 8 weeks after delivery reviewed from May 2017 to April 2018 were investigated with the Edinburgh Postpartum Depression Scale.Results (1) The incidence of postpartum depression was 5.8%, and the incidence of severe postpartum depression was 1.5%. (2) The older the mother, the lower the postpartum depression score, and the difference was statistically significant (P<0.05). There was a negative correlation between age and postpartum depression score (K=-0.066, P<0.001).There was no statistically significant difference in postpartum depression scores among women with different delivery modes and whether there were prenatal complications (P>0.05). (3) Logistic regression analysis showed that low age (OR=0.928, 95%CI: 0.897～0.960) and the occurrence of prenatal complications (OR=1.494, 95%CI: 1.093～2.042) were risk factors of postpartum depression.Conclusion For young pregnant women and/or pregnant women with complications, psychological intervention should be strengthened as soon as possible to avoid postpartum depression.