血清降钙素原、C反应蛋白早期筛查诊断脓毒血症效果研究

doi:10.3969/j.issn.1006-5253.2015.02.009

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Abstract Objective To explore the diagnostic effect of early screening sepsis with procalcitonin (PCT) and C-reactive protein (CRP). Methods Fifty-four patients with sepsis and forty-five healthy patients were respectively collected as the case group and the control group. The indexes of PCT, CRP, WBC and APACHEⅡ score were compared between the two groups. And the sensitivity, specificity, positive predictive value, negative predictive value and accuracy were respectively calculated with PCT, CRP, and PCT in combination with CRP methods. Then, the risk factors of sepsis were analyzed with multiple Logistic Regression method. Results The levels of PCT, CRP, WBC and APACHE Ⅱ scores in the sepsis group were much higher than those in the control group (P<0.01). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of early screening sepsis with PCT in combination with CRP were respectively 92.6%, 84.4%, 87.7%, 90.5%, 88.9%. Multiple Logistic Regression analysis results showed that PCT, CRP, WBC and APACHEⅡ scores were the independent risk factors of the incidence of sepsis. Conclusion These early sepsis patients have a high level of PCT and CRP, and there is high level of sensitivity, specificity and accuracy through early diagnosis.

Key words： Sepsis Procalcitonin C reactive protein Diagnostic test Diagnostic effect

Received: 18 February 2015

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	Gong Jianling

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Gong Jianling. Effect study on early screening sepsis with procalcitonin and C-reactive protein[J]. journal1, 2015, 22(2): 108-110.

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http://manu58.magtech.com.cn/Jwk_zgyytj/EN/10.3969/j.issn.1006-5253.2015.02.009 OR http://manu58.magtech.com.cn/Jwk_zgyytj/EN/Y2015/V22/I2/108

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