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| Study on influencing factors of positive allergens′ number based on logit-NB Hurdle model |
| Liu Yanyan, Li Meng, Yu Lei, Wang Rui, Zhang Maoxiang, Liu Meina |
| Harbin Medical University, Harbin 150086, China |
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Abstract Objective To determine the influencing factors of positive allergen number with zero-inflated data using Hurdle model in order to provide scientific evidence for preventing allergy and allergic disease. Methods The basic information of 1 855 patients who visited allergic apartment in 2014 was collected, the number of specific IgE positive allergen from serum allergen was tested, and logit-NB Hurdle model was used to investigate the influencing factors of positive allergens number. Results
The positive allergens number of 72.29％ patients was 0. Vuong test ( V=3.90 and 2.77, P＜0.05) suggested that Hurdle model was better than traditional counting model, according to LR test and AIC, BIC, and AICC values, and logit-NB Hurdle model was chosen. The result of logit part was that women were more likely to produce allergic reaction than men. The result of zero truncated negative binomial part was that mothers having high education degree were likely to have less positive allergens than those having low education degree, and mothers having a history of allergy could increase the number of positive allergen. Conclusion Analysis of zero expansion of discrete data needs to select the optimal model at first. Women are more likely to produce allergic reaction. People with low education degree and whose mother has a history of allergy should be paid more attention to prevent more allergen numbers.
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Received: 13 July 2015
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