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Risk factors investigation analysis on relapse or metastasis after radical excision of gastric cancer within two years |
Wang Changbiao, Chen Guofu, Jin Dexi |
Gastrointestinal Surgery Department in the First People’s Hospital of Wenling City in Zhejiang Province, Wenling 317500, China |
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Abstract Objective To explore the risk factors of early relapse or metastasis after radical excision of gastric cancer, and to provide basis for preventing and treating gastric cancer patients. Methods One hundred and thirty-nine cases of radical excision of gastric cancer were followed by two years. They were divided into relapse metastasis group (64 cases) and non-relapse metastasis group (75 cases), then single factor and multiple factor analysis methods were used to screen correlated factors of early relapse or metastasis. Results The early relapse rate after radical excision of gastric cancer was 46.0% (64/139). Multiple factors analysis result showed that maximum diameter of tumor (OR=3.764), TNM staging (OR=3.370), serous membrane soakage (OR=8.322), lymphaden metastasis (OR=5.219) and positive number of lymphaden were the risk factors of early relapse after radical excision of gastric cancer, but scavenge scope of lymphaden (OR=0.236) and chemical therapy after operation (OR=0.238) were the protective factors of prognosis. Conclusion The relapse rate after radical excision of gastric cancer is still a little high. These factors such as larger tumor, higher TNM staging, serous membrane soakage, lymphaden metastasis, more positive number of lymphaden, less scavenge scope of lymphaden and without chemical therapy after operation were the independent risk factors of early relapse.
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Received: 21 January 2016
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