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| Case-control study on risk factors of neonatal respiratory distress syndrome of newborns with full-term |
| Zhou Huili, Lu Hongping, Chen Xiaojun |
| Neonatal Department in Taizhou Hospital of Taizhou Enze Medical Center (Group), Taizhou 317000, China |
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Abstract Objective To explore the correlated risk factors of acute respiratory distress syndrome of newborns (NRDS) with full-term, and to provide basis for early intervention for it.Methods Seventy-seven confirmed cases of NRDS were selected as the case group, and 77 cases of normal newborns without NRDS were randomly selected as the control group. With retrospective case-control study method, the risk factors of NRDS were screened by single factor comparison method and multiple factors logistic regression method.Results Single factor analysis showed that there were statistical significances about social factors caesarean section, pregnancy induced hypertension, premature rupture of membranes, meconium pollution in amniotic fluid, fetal intrauterine distress, amniotic fluid inhalation, neonatal infection, asphyxia neonatorum, hypoglycemia in newborns and postpartum use of PS between the two groups (P<0.05). Multiple factors analysis result indicated that the influencing factors of NRDS included social factors caesarean section (OR=5.714), fetal intrauterine distress (OR=6.390), amniotic fluid inhalation (OR=15.745), asphyxia neonatorum (OR=12.798) and postpartum use of PS (OR=0.212).Conclusion The high risk factors of NRDS contain social factors caesarean section, fetal intrauterine distress, amniotic fluid inhalation, asphyxia neonatorum and without use of PS after delivery. To aim directly at these high risk factors, we should early prevent, diagnose and treat NRDS.
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Received: 25 August 2018
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