温州地区189例过敏性鼻炎患者过敏原分布及相关影响因素调查研究

doi:10.3969/j.issn.1006-5253.2018.05.007

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Abstract Objective To investigate the distribution of allergens in 189 patients with (allergic rhinitis, AR) in Wenzhou and to investigate the relevant influencing factors.Methods Immunoblotting was used to detect allergen-specific immunoglobulin E (IgE) antibodies and serum total IgE in AR patients, and at the same time, 370 healthy subjects were selected as the control group. The questionnaires were used to investigate the related factors of AR and compared with the control group. Multivariate logistic regression analysis was also performed.Results All the 189 patients showed positive total serum IgE. The distribution of allergens was the highest in the inhaled allergens, house dust mites, accounting for 51.32%, followed by shrimp, crab and other food allergens, accounting for 14.29%. In 17 influencing factors, 8 factors including history of asthma, history of allergies, smoking, parental allergic rhinitis, floating population, dust or chemical gas contact occupations, daily window ventilation and frequent cleaning had statistically significant difference compared with the control group (P<0.05). Multivariate logistic analysis found that allergic history, smoking, history of asthma, parental allergic rhinitis, floating population, dust or chemical gas contact occupations and pets were AR high risk factors (P<0.05). Daily window ventilation, frequent cleaning and regular exercise were effective protective factors for AR (P<0.05).Conclusion In Wenzhou, house dust mites are the main allergens. The main risk factors are allergic history, history of asthma, pets, parents suffering from AR, and smoking.

Key words： allergic rhinitis influencing factor allergen distribution multivariate logistic analysis positive rate

Received: 28 August 2018

PACS:

R765.21

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	Articles by authors
	Xu Huishuang
	Lü Weizhi
	Yang Yuyan

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Xu Huishuang,Lü Weizhi,Yang Yuyan. Investigation on allergen distribution and related influencing factors in 189 patients with allergic rhinitis in Wenzhou area[J]. journal1, 2018, 25(5): 338-341.

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http://manu58.magtech.com.cn/Jwk_zgyytj/EN/10.3969/j.issn.1006-5253.2018.05.007 OR http://manu58.magtech.com.cn/Jwk_zgyytj/EN/Y2018/V25/I5/338

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