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| Effectiveness evaluation of early HP combined with CVVH treating acute paraquat poisoning |
| Wang Dandan, Dai Wenzhen, Liu Fang |
| The Fourth Wards of Internal Medicine in Luqiao Hospital of Taizhou Enze Medical Center (Group), Taizhou 318050, China |
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Abstract Objective To explore the effect of early HP combined with CVVH treating acute paraquat poisoning (PQ). Methods One hundred and eighty-three patients with PQ were divided into control group (75 cases), HP group (65 cases) and HP+CVVH group (43 cases) according to treatment methods. The survival rates of 3rd, 7th and 60th days were compared among the three groups, and their prognosis effects were analyzed. Results The survival rates of 3rd, 7th, 60th days in the HP+CVVH group were respectively 86.0%, 65.1% and 46.5%, much higher than those in the control group (56.0%, 41.3%, 21.3%, all P<0.05). The survival rates of 3rd, 7th, 60th days in the HP group were respectively 75.4%, 56.9% and 43.1%, much higher than those in the control group (56.0%, 41.3%, 21.3%, all P<0.05). The median survival days of HP+CVVH group and HP group were respectively 40 days and 15 days, both much higher than those the control group (3 days, P<0.01). Conclusion Blood purification techniques (HP, CVVH) could obviously raise median survival days and survival rate of prognosis. Finding out the timing of blood purification and treatment time of acute parquat poisoning could provide basis for clinical popularization.
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Received: 12 October 2016
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