Objective To evaluate the training effect of "guidelines for rational drug use of hypertension for community doctors designed based on current drug use", and to explore the factors influencing training effects of community doctors, so as to provide reference for further improving and perfecting the training of community doctors.Methods A questionnaire survey was conducted to investigate the demographic information, knowledge level for rational hypertension drug administration before and after the training and satisfaction with the community doctors participating in the training. The demographic information and satisfaction level were analyzed with descriptive statistics. The training effect analysis was conducted with Wilcoxon signed-rank test, and influencing factors for training effects were explored with logistic regression.Results Compared with that before the training, the number of wrong answers after the training was significantly reduced (M(P25, P75) as  6(4, 9), P＜0.05). Educational background, marital status and the number of wrong answers before the training were independent influencing factors for the training effect (P＜0.05). The past training opportunities, subjective evaluations, and mastery of professional knowledge of community doctors are significantly correlated with training effectiveness (P＜0.05).Conclusion The effectiveness for this training  was considerable, and most community doctors were satisfied with this training, which indicates that the training designed according to current medication situations and relevant domestic guidelines can effectively improve the knowledge level of community doctors about rational hypertension drug administration.