青春期血压与血清丙氨酸氨基转移酶的关联性分析

doi:10.3969/j.issn.1006-5253.2021.03.004

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Abstract Objective To explore the relationships between the concentrations of serum alanine aminotransferase (ALT) and the levels of systolic（SBP）and diastolic blood pressure（DBP）among adolescents. Methods From February 2018 to June 2019, 7 805 students were enrolled in 9 junior and senior high schools in S〖JP2〗henzhen. Stratified analyses were performed according to gender, age (10-13 years old or 14-17 years old) and serum ALT quartiles (≤ 9 U/L, 10-11 U/L, 12-15 U/L, or >15 U/L). Results The SBP of adolescents was (112.87±12.00) mmHg and average DBP was (71.68±9.61) mmHg among the 7 805 adolescents. The blood pressure of the male group was higher than that of the female group, with SBP (115.81 vs 109.23) mmHg and DBP (73.15 vs 69.86) mmHg (P<0.001); stratified analysis by quartile of serum ALT level showed that blood pressure increased with the increase of ALT level (P<0.001); the generalized additive model showed that there was a correlation between blood pressure and serum ALT level in adolescents, SBP-ALT (r=0.113-0.279, P<0.001), DBP-ALT (r=0.088-0.208, P<0.001); the results of binary logistic regression analysis showed that hypertension was associated with elevated serum ALT (OR=3.411, 95%CI: 2.215-5.251) and boys (OR=3.684, 95%CI:2.594-5.231) among adolescents. Conclusion There is a correlation between elevated blood pressure and elevated serum ALT levels in adolescence, and the local government should increase the vigilance to monitor the simultaneous elevation of blood pressure and ALT in middle school students.

Key words： blood pressure alanine aminotransferase adolescent association

Received: 08 December 2020

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	Articles by authors
	Zhao Yanfei
	Chen Liqiao
	Fang Jiaying
	Ding Zan

Cite this article:

Zhao Yanfei,Chen Liqiao,Fang Jiaying, et al. Relationship between blood pressure and serum alanine aminotransferase among adolescents[J]. journal1, 2021, 28(3): 211-214.

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http://manu58.magtech.com.cn/Jwk_zgyytj/EN/10.3969/j.issn.1006-5253.2021.03.004 OR http://manu58.magtech.com.cn/Jwk_zgyytj/EN/Y2021/V28/I3/211

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