|
|
Epidemiological characteristics and infection pattern of hand-foot-mouth disease among adults in Ninghai County of Zhejiang Province from 2009 to 2019 |
Wang Xiaoying1, Kong Zhifang2, Qin Haiyan1. |
1 Ninghai County First Hospital, Ninghai 315600, China;
2 Ninghai County Center or Disease Control and Prevention, Ninghai 315600, China.
|
|
|
Abstract Objective To study the characteristics and infection pattern of hand-foot-mouth disease (HFMD) in adults, and to provide reference for prevention and control of HFMD in adults. Methods The morbidity data of HFMDadults from 2009 to 2019 were collected from the reporting management system of National Disease Surveillance Information for investigation and follow-up, the epidemiological method was used for statistical analysis, andRT-PCR was used to detect enterovirus nucleic acid of stool samples of patients and family members collected. Results From 2009 to 2019,208 cases of adultswith HFMD were collected in Ninghai County. The incidence rate was high every other year, with females higher than males, and the occupation was dominated by farmers. The analysis of clinical characteristics showed that heat degree of children with fever was higher than that of adults, and skin rash, pain, peeling, and depigmentation were significantly higher in adults than in children,both of which were statistically significant.Analysis of factors of HFMD in adults and children showed no statistical significance in family size and per capita living area. There were significant differences in gender, living type, family with children under 5 years old, family with patients with HFMD recently, eating together, and sharing mobile phones.There are many infection patterns in adult HFMD, and child-adult mode is the main infection pattern in adults with HFMD. Conclusion Adults with HFMD also has a higher incidence. Etiological detectionshowed that all virus types can cause HFMD in adults. CVA6 is the main type of infection. childparent transmission is the main mode of infection in adults.
|
Received: 18 March 2020
|
|
|
|
[1]李静,戴莹,雷亚克,等.人类肠道病毒7l型研究进展[J].公共卫生与预防医学,2012,23(1):59-61.
[2]WANG Y,SUN L,XIAO W,et a1.Epidemiology and clinical characteristics of hand foot,and mouth disease in a Shenzhen sentinel hospital from 2009 to 20l1[J].BMC Infect Dis,2013,13(1):539-543.
[3]ZHAO J,JIANG F,ZHONG L,et al.Age patterns and transmission characteristics of hand.foot and mouth disease in China[J].BMC Infect Dis,2016,16(1):691.
[4]郭悦,韩桃利,黄晓霞,等.2008—2016年我国手足口病突发公共卫生事件报告分析[J].病毒学报,2017,33(6):880-885.
[5]邹宏超,曹兰,朱薇,等.30例成人手足口病患者及病毒学研究[J].皮肤病与性病,2016,38(6):397-399.
[6]平东兰,祁文涛,赵思,等.50例成人手足口病病例发病及治疗效果分析[J].医学动物防治,2014,30(3):338-340.
[7]Centers for Disease Control and Prevention(CDC).Notes from the field:severe hand,hand,foot,and mouth diseased associated with coxsackievirus A6Alabama,Connecticut,California,and Nevada,November 2011-February 2012[J].MMWR Morb Mortal WklyRep,2012,61(12):213-214.
[8]CHANG L Y,TSAO K C,HSIA S H,et al.Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan.JAMA,2004,291:222-227.
[9]SECOND J,VELTYER C,CALES S,et a1.Clinicopathologic analysis of atypical hand,foot,and mouth disease in adult patients [J].J Am Acad Dermatol,2017,76(4):722-729.
[10]CHATPROEDPAI S, TEMPARK T,WANLAPKORN N,et al.Unusual skin manitestation of hand,foot and mouth disease associated with coxsackievirus A6:cases report[J].Springerpius,2015,17(4):362.
[11]YANG F,YUAN J,WANG X, et al.Severe hand,foot,and mouth disease and coxsackievirus A6Shenzhen,China[J].Clin Infect Dis,2014,59(10):1504-1505.
[12]National Health Commission of the People’s Republic of China. Diagnostic Criteria forhandfootandmouth disease (WS 588-2018); National Health Commission of the People’s Republic of China: Beijing, China, 2018.
[13]孔志芳,杨斌,章海斌,等.2009—2018年浙江省宁海县手足口病流行特征及病原学分析[J].中国医院统计,2019,26(5):373-376.
[14]CHENG K T,CHANG H L,WANG S T,et al.Epidemiologic features of handfootmouth disease and herpangina caused by enterovirus 71 in Taiwan,1998-2005.Pediatrics,2007,120:e244-252.
[15]ZENG M,E1 KHATIB N F,TU S,et al.Seroepidemiology of Enterovirus 7l infection prior to the 2011 season in children in Shanghai.J Clin Virol,2012,53:285-289.
[16]张海泉.2016年滨州市手足口病流行病学特征及病原学监测分析[J].中国医院统计,2018,25(5):327-329. |
[1] |
Wang Qian,Li Fan,Ding Guofeng. Clinical characteristics and risk factors of lower respiratory tract infection of adults in rural community[J]. journal1, 2019, 26(5): 337-339. |
[2] |
Kong Zhifang, Yang bin, Zhang Haibin,Hu Lili, Zhang Dan, Chen Wei, Wang Fan, Ge Baoxiang.. Epidemiological characteristics and pathogenicity study of hand foot and mouth disease in Ninghai County of Zhejiang Province from 2009 to 2018[J]. journal1, 2019, 26(5): 373-376. |
[3] |
Hong Min. Investigation on the cognition of caregivers of children with hand-foot-mouth disease in the Community of Gongchenqiao[J]. journal1, 2019, 26(1): 69-71. |
[4] |
Zhang Haiquan. Analysis of epidemiological and etiological characteristics of hand-foot-mouth disease in Binzhou city in 2016[J]. journal1, 2018, 25(5): 327-329. |
[5] |
Zhou Lizhen, Zhao Xuepin. Survey analysis on characteristics and correlated risk factors of prognosis of children severe hand foot and mouth disease[J]. journal1, 2018, 25(1): 17-19. |
[6] |
Zhang Yupei, Zhang Liguo, Ding Guofeng.. Epidemiological surveillance of hand, foot and mouth disease in a hospital in Binzhou from 2010 to 2015[J]. journal1, 2017, 24(2): 85-87. |
|
|
|
|