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Establishment and evaluation of a pharmaceutical intervention procedure for chronic pulmonary disease patients with dry powder inhalers |
Shi Dongming1, Xu Haofeng1, Yang Huajun1, Du Junwei2, Ye Xiaofen3 |
1 Department of Pharmacy, the First Hospital of Fuyang District, Hangzhou 3114002, China; 2 Deparment of Respiratory Medicine, the First Hospital of Fuyang District; 3 Department of Pharmacy, Zhongshan Hospital, Fudan University |
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Abstract Objective To evaluate the effect of pharmaceutical intervention procedures on the efficacy of dry powder inhalers in patients with chronic pulmonary disease by establishing a standard model.Methods Patients in the intervention group were consecutively intervened for 6 months using the established pharmacological intervention procedure and evaluation criteria. The control group received only routine follow-up. The DPI operating score, lung function index, symptom self-assessment, disease control, drug-related knowledge and number of patients in emergency were evaluated before and after the treatment for the two groups.Results In the intervention group, after 6 months of pharmacological monitoring, the inhalation device operation score and CAT/ACT score of the patients with chronic obstructive pulmonary disease (COPD) were significantly improved compared with the control group (t=3.790, 4.661, P<0.05). The difference was also significant compared with the control group (q=3.108, 2.539, P<0.05). After 6 months of treatment for asthma patients, the inhalation device operation score, FEV1% predicted value, and ACT score of the intervention group were significantly higher than those of the control group (t=4.622, 3.912, 7.418, P<0.05). The difference between the two groups was also significant (q=2.698, 2.089, 2.264, P<0.05). In addition, the number of patients in the intervention group was significantly lower than that that in the control group (χ2=4.85, P<0.05), and the scores of the drug-related knowledge questionnaires were significantly higher than those in the control group (χ2=6.68, P<0.05). The number of people with good adherence was higher than that in the control group (χ2=8.15, P<0.05).Conclusions The establishment of standard medication intervention procedure for inhalants can improve the standardization and effectiveness of inhalation therapy, stabilize disease progression, and have good practical and scientific value in disease management and treatment.
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Received: 12 July 2018
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