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Risk factor analysis of IFIS in age related cataract surgery |
Wen Jiquan1, Hong Mingsheng1, Chen Yidan2, Cao Yongbao1, Xu Jiehui1 |
1 Ophtalmology Department, Zhejiang Hospital, Hangzhou 310013, China; 2 Acupuncture Department, Zhejiang Hospital |
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Abstract Objective To explore the risk factors of intraoperative floppy-iris syndrome (IFIS), so as to provide evidence for its clinical prevention and treatment. Methods Totally 482 patients (554 eyes) with age related cataract treated in the hospital were analyzed retrospectively, in which 53 patients (56 eyes) occurred IFIS. The clinical data of all the patients were analyzed, and the risk factors of IFIS were established by single factor analysis and logistic regression analysis. Results Single factor analysis results showed that age, sex, body mass index, alpha 1 receptor antagonist medication history (including tamsulosin, dorsey azole oxazine, terazosin and alfuzosin), benzodiazepines drug medication history, and antipsychotic drug history were likely to affect the incidence of IFIS in cataract ultrasonic emulsification surgery (P<0.05), while visual acuity, intraocular pressure, duration, cataract nucleus hardness grading, complications and surgical type had no significant difference (P>0.05). Logistic regression analysis results showed that 70 years old and above (OR=2.079), alpha 1 receptor antagonist medication history, benzodiazepines drug medication history and antipsychotic drug history were risk factors of IFIS (P<0.05, OR>1.0). Conclusion This study systematically summarizs the influence factors and risk factors of IFIS of senile cataract surgery, and has a certain guiding significance for the clinical prevention and treatment of IFIS.
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Received: 31 August 2017
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