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Investigation analysis of correlated risk factors of relapse after operation about bladder carcinoma |
Pan Diqing, Dong Xuecheng |
Urinary Surgery Department in the Sixth People′s Hospital of Cixi, Cixi 315300, China |
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Abstract Objective To explore the relapse rate and correlated risk factors of bladder carcinoma after operation. Methods One hundred and fifty-eight patients with bladder carcinoma operation were divided into relapse group and without-relapse group, through 3 years following-up. Correlated risk factors that could affect relapse after operation were collected, and risk factors were screened by single factor and multiple factors analysis methods. Results The relapse rate of bladder carcinoma after 3 years′ operation was 26.6 percent (42/158). Single factor analysis showed that the factors of tumor grading, tumor staging, tumor size, tumor amount, operation styles, lymphatic metastasis and adjuvant chemotherapy after operation affected the relapse of bladder carcinoma after operation. Multiple factors analysis results showed that the risk factors of bladder carcinoma after operation included in tumor grading (OR=2.632), tumor staging (OR=2.690), operation styles (OR=2.936) and lymphatic metastasis (OR=9.935), but adjuvant chemotherapy after operation was the protective factor of bladder carcinoma after operation. Conclusion The independent risk factors of bladder carcinoma after operation include muscle invasive bladder cancer, higher tumor grading or staging of tumor, partial cystectomy, incidence of lymphatic metastasis and adjuvant chemotherapy after operation.
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Received: 28 July 2015
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