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| Clinical and imaging studies of pulmonary benign metastasizing leiomyoma |
| WANG Min1, LIU Jian1, ZHANG Zhiqiang1, QI Kai2, WANG Shuo3, WANG Liangjie1 |
1 Department of Radiology,Zibo Central Hospital,Zibo 255036, P.R.China;
2 Department of Radiology,Zhangdian District People's Hospital of Zibo;
3 Department of Urology department, Zibo Central Hospital |
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Abstract Objective To study the clinical and imaging findings of pulmonary benign metastasizing leiomyoma.Methods The clinical and imaging findings of 21 cases of PBML in China and 1 case of PBML in our hospital were summarized and analyzed.Results All PBML patients were female,with an average age of 44 years.All patients had a history of uterine leiomyoma surgery.50% of the PBML cases were found in physical examination.The time from the first uterine fibroids operation was from 1 month to 23 years, and the median time was 10 years. The imaging findings were as follow: double lung or single lung multiple nodules in 82% cases; 5% showed bilateral lung scattered in miliary tubercle;5% combined with subpleural mass;9% combined with other site metastasis and bone destruction; all cases had no lymph node enlargement and pleural effusion; in 3 enhanced scan cases,2 cases showed significant enhancement, and 1 case showed no enhancement; 4 cases underwent PET-CT, while there were no obvious radioactivity. 86% cases ER and PR were (+), 5% was only ER (+),and 5% was only PR (+).Conclusion Most of the PBML patients are women of childbearing age, most of which have the history of hysteromyoma surgery. There are no obvious clinical symptoms, and the imaging features are not typical, just like double lung metastasis.Therefore, women with childbearing age have several lesions in the lungs after myomectomy for several years. We should take BML into account without the history of malignant tumors.
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Received: 09 August 2018
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