Objective To explore the risk factors of acute kidney injury (AKI) in critically ill patients.Methods In a prospective nested casecontrol study, critically ill patients who were admitted to the ICU ward of a tertiary hospital were followed up as a cohort. They were divided into the case group and the control group according to the acute kidney injury, and the clinical basic characteristics of both groups were compared. Multivariate logistic regression was used to analyze the influencing factors of AKI in critically ill patients.Results Totally 426 critically ill patients meeting the inclusion criteria entered the cohort, with 112 patients in the case group and 314 patients in the control group. There were significant differences between both groups in gender, age, APACHE II score, number of extrarenal organ failure, severe infection, CKD, hypertension, diabetes, surgery, arterial oxygen partial pressure, lactic acid, blood calcium, serum creatinine, platelets, blood urea nitrogen, serum creatinine, aspartate aminotransferase, and brain natriuretic peptide (P<0.05). Multivariate logistic regression analysis showed that the risk factors for AKI of critically ill patients included age, APACHE II score, and extrarenal organ failure. number, severe infection, CKD, surgery, serum creatinine, and brain natriuretic peptide, with the probability lower than 0.001.Conclusion Old age, high APACHE II score, extrarenal organ failure, severe infection, CKD, surgery, elevated serum creatinine, and elevated brain natriuretic peptide were major risk factors for AKI of critically ill patients, and the abovementioned abnormal indicators suggest increased risk of AKI in patients, so attention should be paid in the c
Objective To explore the clinical features and correlated risk factors analysis on the incidence of hypoglycemia in newborns. Methods Totally 312 newborns with hypoglycemia were chosen as the hypoglycemic group, and 312 newborns
Objective To explore the related risk factors and prevention and treatment measures of neonatal respiratory failure.Methods Totally 186 neonates with respiratory failure and 188 neonates without respiratory failure in the intensive care unit admitted to our hospital from January 2016 to December 2018 were collected, and the number of primary diseases and related factors of neonatal failure in the two groups were compared.Results The proportion of rural children, preterm delivery, cesarean section, multiple pregnancy, intrauterine distress and pregnancy complications in the study group were higher than those in the control group, and the difference was statistically significant (P<0.05). Among the primary diseases of neonatal respiratory failure, the proportions of amniotic fluid aspiration pneumonia, meconium aspiration syndrome, respiratory distress syndrome, congenital heart disease and birth asphyxia in the study group were higher than those in the control group, with statistically significant differences (P<0.05). The results of logistic multivariate analysis showed that preterm delivery, cesarean section, amniotic fluid aspiration pneumonia, respiratory distress syndrome and birth asphyxia were the independent risk factors of neonatal respiratory failure (P<0.05).Conclusion The cause of neonatal respiratory failure is related to many factors, so it is necessary to strengthen the monitoring of the living place, premature delivery, cesarean section, amniotic fluid aspiration pneumonia, respiratory distress syndrome, birth asphyxia and other risk factors.
Objective To explore factors related to hormone replacement therapy (HRT) in compliance of patients with climacteric syndrome.Methods A retrospective analysis was conducted on 105 patients with climacteric syndrome who received hormone replacement therapy from February 2014 to March 2018 in our hospital. The differences of factors affecting patients' HRT compliance were compared.Results Of the 105 patients, 40 (38.09%) had poor compliance and 65 (61.91%) had good compliance. Univariate analysis showed that education level, occupation, economic income, marital status, cognition, family support, medical expenses, medical conditions, adverse reactions and doctor-patient relationship all had significant effects on patient HRT compliance. Logistic regression analysis showed that low level of education, manual labor occupation, poor economic income, single marital status, lack of cognitive status, lack of family support, selfpay for medical expenses, inconvenient medical conditions, adverse reactions and poor doctorpatient relationship were risk factors for poor HRT compliance.Conclusion There are numerous factors affecting HRT compliance in menopausal syndrome. It is necessary to improve the compliance of HRT by combining the actual situation of patients and implementing targeted measures.