Home  |  About Us  |  Editorial Board  |    |  Subscribe  |  Messages Board  |  Contact Us  |  中文   Office Online Online Submission Peer Review Office Work   Journal Online    Forthcoming Articles    Current Issue    Archive    Read Articles    Download Articles    Email Alert     2018 Vol. 25, No. 4 Published: 2018-08-25   241 Short-and long-term outcomes of laparoscopic hepatectomy for elderly patients with colorectal liver metastases Chai Lixin, Pan Zhijian, Wu Wei, Bai Guang DOI: 10.3969/j.issn.1006-5253.2018.04.001 Objective To evaluate the short-and long-term outcomes of laparoscopic hepatectomy (LH) for colorectal liver metastases (CRLM) in elderly patients. Methods From January 2010 to January 2017, LH was performed for consecutive 207 patients who were 60 years old and above and had CRLM. Based on their age at the LH, the patients were divided into the elderly group (70 years old and above, 68 patients) and the middle-aged group (from 60 to 69 years old, 139 patients). The short-term and long-term outcomes were compared between the two groups. Results Compared to the middle-aged group, the elderly group had higher values for age, Charlson comorbidity index, proportion of preoperative chemotherapy, and American Society of Anesthesiologists score. No other significant differences were observed in the preoperative data. The elderly group had a higher conversion rate, compared to the middle-aged group, although no significant differences were observed in the surgical procedures, surgical time, intraoperative blood losses, numbers and severities of postoperative 90-day complications, postoperative 90-day mortality rates, pathology results, and other short-term outcomes. Long-term follow-up revealed similar rates of recurrence, disease-free survival, and overall survival in the two groups. Multivariate analysis revealed that age did not independently predict overall survival or disease-free survival. Conclusion Similar short-and long-term outcomes were observed after LH for CRLM in elderly and middle-aged patients. Thus, advanced age is not a contraindication for LH treatment in this setting. 2018 Vol. 25 (4): 241-244 [Abstract] ( 60 ) HTML (1 KB)  PDF (960 KB)  ( 123 ) 245 Meta-analysis of wuziyanzong and levocarnitine for male infertility He Fangxiang, Mao Xiongwei, Wu Hui DOI: 10.3969/j.issn.1006-5253.2018.04.002 Objective To systematically evaluate the efficacy of wuziyanzong and levocarnitine in the treatment of male infertility. Methods Based on the principles and methods of Cochrane systematic reviews, we searched PubMed, Embase, the Cochrane Library, EBSCO, CNKI, VIP, CBM and Wanfang databases from inception to July 2017 for randomized controlled clinical trials addressing the treatment of male infertility with wuziyanzong. According to the inclusion and exclusion criteria and retrieval strategies, we extracted the data, evaluated the quality of the included literature, and conducted meta-analysis using the RevMan 5.3 software. Results Four trials involving 324 patients were included. The results of meta-analysis showed that effectiveness rate(RR=1.25,95%CI:0.99~1.58,P=0.06), confirmed pregnancy rate(RR=1.76,95%CI:0.81~3.82,P=0.15), △semen volume(MD=-0.04,95%CI:-0.41~0.34,P=0.85), △sperm density(SMD=0.65,95%CI:-0.12~1.43,P=0.10), △grade A sperm rate(MD=1.89,95%CI:-10.41~14.20,P=0.76)and △grade A+B sperm rate(MD=3.42,95%CI:-5.00~11.84,P=0.43) of wuziyanzong group were not inferior to those of levocarnitine group, but △sperm motility of wuziyanzong group was inferior to that of levocarnitine group (MD=-12.42,95%CI:-22.06~ -2.78,P=0.01). Conclusion According to this evaluation system, wuziyanzong treatment of male infertility has some curative effect, but because of some limitations, it still needs large-scale randomized controlled clinical trial for verification according to dialectics of traditional Chinese medicine. 2018 Vol. 25 (4): 245-249 [Abstract] ( 61 ) HTML (1 KB)  PDF (1540 KB)  ( 181 ) 250 Application of Bishop score in vaginal delivery of scarred uterus Qian Jingjing, Chen Yuanyuan DOI: 10.3969/j.issn.1006-5253.2018.04.003 Objective To study the feasibility of using the Bishop score as a sign of vaginal delivery in pregnant women with scar uterus, and to analyze the application value of the Bishop scoring system in the judgment of the timing of the labor in the scar uterus. Methods Totally 120 pregnant women with scar uterus were selected who were to be delivered in our hospital from April 2017 to December 2017. According to the Bishop score, the parturients were divided into high score group (Bishop score>3) and low score group (Bishop score≤3). The delivery mode, duration of labor, hospitalization time and intrapartum bleeding of two groups were recorded, and the pregnancy complications of the two groups were analyzed. Results The vaginal delivery rate of the high score group (73.58%) was higher than that of the low score group (31.34%), and there were statistically significant differences between the two groups (χ2=21.121,P<0.001). The length of hospitalization time of the high score group [(9.53±2.14) h] was shorter than that of the low scrore group [(10.23±2.14) h], production hemorrhage of the high score group [(158.21±30.12) ml] was less than that of the low score group [(492.23±90.86) ml], and there were significant differences between the two groups (P< 0.05). The incidence of postpartum hemorrhage (9.43%) was lower than that in Lower group (25.37%), and there were statistically significant differences between the two groups (P<0.05). The incidence of fetal distress in the high score group (11.32%) was lower than that of the low score group (28.36%), and there were significant differences between the two groups (P<0.05). Conclusion Pregnant women with scar uterus can undergo vaginal trial production. The rate of vaginal delivery in pregnant women with high Bishop scores is higher, and the incidence of postpartum and neonatal complications is low. The Bishop score can be used as an indication for vaginal delivery in pregnant women with scarred uterus. 2018 Vol. 25 (4): 250-252 [Abstract] ( 53 ) HTML (1 KB)  PDF (946 KB)  ( 138 ) 253 Influence factors of saprodontia in preschoolers Yao Xufei DOI: 10.3969/j.issn.1006-5253.2018.04.004 Objective To explore the influence factors and controlling measure of saprodontia in preschoolers. Methods Totally 785 preschoolers were selected with cluster sampling method, and information on children and their family was recorded by self-control questionnaire scale. The influence factors were analyzed by SPSS 20.0, and both protective factors and risk factors were established by logistic regression. Results There were 737 valid questionnaire scales in all, and the recovery rate was 93.9%, with the saprodontia rate 38.5% and the saprodontia average 2.53. Children age, birth body mass, gestation length, feeding patterns, sweetmeat and beverages frequency, brush teeth age, brush teeth frequency, oral inflammation during pregnancy, gestational diabetes mellitus, calcium supplement during pregnancy, parent saprodontia and whether to do children's oral examination regularly were all influence factors of saprodontia (P<0.05). The aged five and above, low birth weight infant, frequent sweetmeat, brushing frequency less than one time a day, oral inflammation during pregnancy and parent saprodontia were risk factors for children saprodontia (P<0.05). And breast feeding, calcium supplement in gestation period and do children′s oral examination regularly were all protection factors for children saprodontia (P<0.05). Conclusion Children have high caries rate, and increasing health promotion and improving the nursing care awareness of parents is one of the effective means to control children's dental caries. 2018 Vol. 25 (4): 253-256 [Abstract] ( 71 ) HTML (1 KB)  PDF (1002 KB)  ( 210 ) 257 Thyroid hormone level analysis of island area pregnant women in different pregnant periods and gestational age Wu Xianfeng, Xu Haigeng DOI: 10.3969/j.issn.1006-5253.2018.04.005 Objective To analyze thyroid hormones changes of island area pregnant women in different pregnant periods and gestational age. Methods Totally 3000 healthy pregnant women in island area were taken as the observation group and 600 healthy pregnant women were taken as the control group. The levels of serum total triiodothyronine (TT3), total thyroxine TT4, free FT3, FT4 and TSH levels were compared in different pregnant periods and gestational age. Median (M) and bilateral limit (P2.5, P97.5) were adopted to indicate reference range for thyroid hormone levels Results Compared with the control group, the levels of TT3 and TT4 in the early, middle and late stage of pregnancy increased significantly (P<0.05). The levels of FT3 and FT4 in early, middle and late stage of pregnancy and the levels of TSH in early and middle stage of pregnancy were lower significantly (P<0.05). TT3 and TT4 in 20 to 30 years old, 31 to 35 years old and 36 to 45 years old groups were much higher than those of the control group (P<0.05). FT3, FT4 and TSH were significantly lower than those of the control group (P<0.05). Levels of FT3, FT4 and TSH were significantly different between 20 to 30 years old group and 36 to 45 years old group, and there was no significant difference between 31~35 years old group and 36~45 years old group (P>0.05) as to various indicators. Conclusion The thyroid hormones during pregnancy change obviously in different gestational stages, and have close relationship with gestational ages. Pregnant women, especially those over 35 years old, should carry out thyroid function tests as early as possible to reduce the incidence of adverse pregnancy outcomes and improve our population and reproductive quality. 2018 Vol. 25 (4): 257-259 [Abstract] ( 61 ) HTML (1 KB)  PDF (950 KB)  ( 131 ) 260 Effect of preoperative anxiety on postoperative recovery of elderly patients with hip fracture Xiao Shanjie DOI: 10.3969/j.issn.1006-5253.2018.04.006 Objective To investigate the effect of anxiety on postoperative recovery in elderly patients with hip fracture and to explore the influencing factors of anxiety. Methods The questionnaire was compiled, combined with the self rating Anxiety Scale and the Harris scale of the hip joint treatment effect. The data were obtained from the 84 cases of elderly patients with hip fracture treated in Department of orthopedics at a hospital from January to December of 2017 including personal information, anxiety and Harris scores. Results 52.4% of the elderly patients with hip fracture were in anxiety. The Harris scores in the anxiety group and the normal group were statistically significant (P<0.05). The incidence of anxiety in patients with different gender, marital status, children′s residence, cause of injury and source of income was statistically significant. Conclusion Anxiety can affect postoperative recovery in elderly patients with hip fracture. Marital status, cause of injury and source of income are important causes of anxiety in elderly patients with hip fracture. These patients should be targeted for psychological care before operation. 2018 Vol. 25 (4): 260-262 [Abstract] ( 51 ) HTML (1 KB)  PDF (933 KB)  ( 145 ) 263 Application study on smecta plus befuxin combined with exposure therapy in neonatal hip redness Zhang Xiaoli, Mu Feifei DOI: 10.3969/j.issn.1006-5253.2018.04.007 Objective To explore the therapeutic effect of befuxin plus smecta combined with exposure therapy on neonatal hip redness. Methods A total of 46 cases of buttock redness occurred in the neonatal children admitted to our hospital, which were divided into the control group and the experiment group according to the order of admission. Children in the control group were treated with smecta, and those in the experiment group were treated with smecta plus befuxin combined with exposure therapy. Results The apparent efficiency of the experiment group was 86.96% and the effective rate was 13.04%, while the apparent efficiency of the control group was 60.87%, and the effective rate was 30.43%. The therapeutic effect of the experiment group was better than that of the control group (P<0.05). The healing time of the experiment group [(102.29 + + 61.34)h] was less than that of the control group [(142.52 + 60.23)h], and the comparison of healing time between the two groups was statistically significant (P<0.05). Conclusion Befuxin plus smecta combined with exposure therapy has a significant effect in the treatment of newborn buttock redness. It can effectively shorten the healing time of skin rash and is safe and reliable. 2018 Vol. 25 (4): 263-264 [Abstract] ( 46 ) HTML (1 KB)  PDF (925 KB)  ( 149 ) 265 Clinical characteristics of fulminant type 1 diabetes mellitus, acute onset type 1 diabetes and slowly progressive type 1 diabete Zhong Xiaojing, Li Shunbin, Jin Yueping DOI: 10.3969/j.issn.1006-5253.2018.04.008 Objective To analyze the clinical features of 20 patients with acute onset type 1 diabetes (AT1DM), 11 patients with fulminant type 1 diabetes (FT1DM) and 23 patients with chronic onset type 1 diabetes (SPIDDM). Methods Data such as disease course, age, gender, body mass index, random blood glucose, HbA1c, C-peptide, creatinine, serum potassium, arterial blood pH, and white blood cell count were collected for statistical analysis, and the clinical characteristics of each subtype were further compared. Results The course of FT1DM was[(4.23±1.21)days] shorter than those of AT1DM[(146.25.±33)days] and SPIDDM[(518.2±64.6)days]. The blood glucose concentration at the onset of FT1DM[(38.23±15.41)(mmol/l)] was higher than those of AT1DM [(16.75±4.88)(mmol/l)] and SPIDDM[(13.44±4.12)(mmol/l)]. The FT1DM glycosylated hemoglobin concentration[(6.58±1.66)(mmol/l)] was lower than those of AT1DM[(12.83±3.81)(mmol/l)] and SPIDDM[(11.01±3.21)(mmol/l)]. The mean blood glucose concentration fluctuation range of FT1DM[(9.55±2.40) (mmol/l)] was higher than those of AT1DM[(5.54±1.84) (mmol/l] and SPIDDM[(5.13±1.31)(mmol/l). The difference between the maximum and minimum blood glucose concentration of FT1DM[(13.54±3.227)(mmol/l)] was higher than those of AT1DM[(7.46±3.44)(mmol/l)] and SPIDDM[(6.92±2.37)(mmol/l)]. Arterial blood pH of FT1DM (7.003±0.083) was lower than those of AT1DM (7.393±0.095) and SPIDDM (7.395±0.038). The fasting C-peptide concentration[(0.03-0.02)(ng/ml)] of FT1DM was lower than those of AT1DM[(0.91±0.43) (ng/ml)] and SPIDDM[(1.05±0. 47) (Ng/ml)]. The differences between the above indicators were statistically significant (P<0.01). Conclusion Compared with AT1DM and SPIDDM, FT1DM has a shorter duration of disease, greater fluctuations in mean blood glucose, more severe ketoacidosis, poorer islet function, and the more dangerous condition. 2018 Vol. 25 (4): 265-267 [Abstract] ( 55 ) HTML (1 KB)  PDF (948 KB)  ( 124 ) 268 Investigation on characteristics and correlated risk factors of hospital infection of acute myocardial infarction Shen Qunhe, Ye Hongbo, Huang Danhong DOI: 10.3969/j.issn.1006-5253.2018.04.009 Objective To explore the characteristics and correlated risk factors of hospital infection of acute myocardial infarction. Methods Data of 424 cases with AMI were retrospectively analyzed, these cases were divided into the infection group (56 cases) and the non-infection group (368 cases) according to whether or not with hospital infection. Single factor and multiple risk factors methods were used to screen the risk factors of AMI hospital infection. Results The hospital infection rate of AMI was 13.2% (56/424), mainly in respiratory system and urinary system. Multiple factors analysis result showed that these factors such as combination with basic diseases (OR=4.802, 95%CI:3.381~6.223, P<0.001), heart failure (OR=2.565, 95%CI:1.648~3.482, P=0.004), invasive procedure (OR=5.618, 95%CI:4.017~7.219, P=0.003), use of respirator (OR=1.878, 95%CI:1.213~2.542, P<0.001) and antibacterials (OR=2.815, 95%CI:1.657~3.973, P=0.019) were the risk factors of hospital infection of AMI. Conclusion The hospital infection rate of AMI is high, mainly with respiratory tract infection. We should early monitor, prevent and treat the hospital infection to aim directly at these above independent risk factors, and formulate reasonable intervention measures, in order to cut down hospital infection rate of AMI. 2018 Vol. 25 (4): 268-270 [Abstract] ( 62 ) HTML (1 KB)  PDF (947 KB)  ( 145 ) Copyright © Editorial Board of journal1 Supported by:Beijing Magtech