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Risk factors of multidrug-resistant bacterial infection of patients in the department of infectious disease |
Wu Hongdi |
Infection Dept., Tongde Hospital of Zhejiang Province, Hangzhou 310012, China |
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Abstract Objective To explore the risk factors of multidrug-resistant bacterial (MDRB) infection of patients in the department of infectious disease and nursing strategy.Methods A retrospective study was carried out in 150 patients with bacterial infections in the department of infectious disease from the hospital. Eighty-seven cases were with MDRB infection and belonged to the MDRB group, and remaining 113 cases were not with MDRB infection and belonged to the non-MDRB group. Single factor analysis and binary logistic analysis were used to analyze clinical data relations with the MDRB infection, in order to identify risk factors. The nursing strategy was made according to the risk factors.Results The differences in age, diabetic nephropathy, heart failure, dialysis age, length of stay, skin infection and antibacterial drug combination trauma, operation, length of stay, mechanical ventilation, central venous catheteration, indwelling catheter (gastric tube, urinary catheter and so on), parenteral nutrition and use time of broad-spectrum antimicrobial agents between the MDRB group and the non-MDRB group were statistically significant (P<0.05). The binary logistic analysis showed that operation (OR:3.587 95%CI:1.687~7.627), length of stay≥7 (OR:14.466,95%CI: 6.900~30.329), central venous catheteration (OR:2.853,95%CI:1.025~7.940), indwelling catheter (gastric tube, urinary catheter and so on) (OR:2.848,95%CI:1.550~5.231) and use time of broad-spectrum antimicrobial agents≥3 (OR:10.423,95%CI:5.336~20.360) were the risk factors of MDRB infection (P<0.05).Conclusion The risk factors of patients with MDRB infection in the department of infectious disease indicated that medical staff should pay close attention to MDRB infection status of high-risk patients, in order to reduce the MDRB infection rate.
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Received: 17 April 2018
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