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滨州医学院学报
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2017 Vol. 40, No. 5
Published: 2017-10-15
321
Clinic effects on comparison of femtosecond laser-assisted cataract surgery and conventionalphacoemulsification in patients with cataract
XU Chang, JIANG Yaqin, SHI Yuan, HUANG Xudong
Objective
To study the visual quality of femtosecond laser-assisted cataract surgery and conventional phacoemulsification in patients with cataract.
Methods
In this case-control study,a total of 83 patients were randomly divided into study group (52 eyes) and control group (48 eyes).Postoperative 1 day,1 week,1 month measured 2 groups of patients the best corrected visual acuity (BCVA),iTrace visual function analyzer is used to measure the two naturally take group a high order aberration of the pupil diameter is 3 mm (total eye High order aberration,Spherical,coma,trefoil) and total higher-order aberration of the modulation transfer function (MTF).Data using the single factor analysis of variance.
Results
Two groups of BCVA 1 d after surgery,there were differences in postoperative 1 week, there was statistical significance,no obvious difference was found between postoperative BCVA of 1 month, no statistical significance.After 1 day,1 week,1 month experimental eyes naturally made full eye pupil diameter of 3 mm total eye High order aberration,Spherical,coma,trefoil was better than that of control group,with statistical significance,high-order aberration of MTF was better than that of control group,with statistical significance.After 1 day,1 week,1 month, all experimental surgery eye the mean total higher-order aberrations was lower than the control group,both groups showed a trend of decline over time,and both the mean gradually close to change over time.Postoperative 1 day,1 week,1 month experimental technique under the eye always higher-order aberrations of MTF average higher than that of control group,both groups showed a trend of increasing over time, and the average change over time approaching.
Conclusion
The femtosecond laser-assisted cataract surgery compared with the conventional phacoemulsification cataract surgery has better visual quality. The femtosecond laser-assisted cataract surgery has a great clinical effects which improve patients visual quality early.
2017 Vol. 40 (5): 321-325 [
Abstract
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191
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326
Ahmed glaucoma valve implantation combined with 1.8mm-incision phacoemulsification for refractoryglaucoma coexisting cataract
MA Jianli, WANG Jibing, ZHANG Min, JIANG Yaqin
Objective
To evaluate the efficacy and safety of Ahmed valve implantation combined with 1.8 mm-incision phacoemulsification in the treatment of patients with medically uncontrolled glaucoma coexisting cataract.
Methods
The authors retrospectively reviewed the records of 21 consecutive patients with refractory glaucoma incorporated cataract who underwent a 1.8 mm-incision phacoemulsification combined with placement of an Ahmed valve implant.Control of intraocular pressure (IOP),pre-and postoperative best-corrected visual acuity,corneal curvature and the development of intra-and postoperative complications were evaluated during the follow-up.
Results
The mean follow-up was 11.7 months (range,8 to 21 months). Mean preoperative IOP was (37.9 ± 10.2) mmHg and mean postoperative IOP at the last visit was (14.3 ±5.8) mmHg (
t
=9.19,
P
＜0.01).Two patients needed antiglaucoma medication.Postoperative visual acuity improved in all 21 eyes, and the best-corrected visual acuity in these eyes improved from (0.19±0.11) to (0.57 ±0.14) (
t
=11.45,
P
＜0.01).The preoperative corneal curvature was (0.80±0.21) D while the postoperative corneal curvature was (0.78±0.3) D (t=0.19,
P
=0.85).The early complications occurred were transient hypotony with choroidal detachment in one case, which amended within 1 week and microscopic hyphema in 2 patients which disappeared the second day. The main late postoperative complication was an encapsulated bleb, which occurred in 2 patients and led to high IOP.
Conclusion
The combination of 1.8 mm-incision phacoemulsification combined with placement of an Ahmed valve implant is safe and effective in uncontrolled glaucoma incorporated cataract.
2017 Vol. 40 (5): 326-329 [
Abstract
] (
139
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330
Effective safety analysis and prognosis evaluation of traditional Chinese medicine combined withacupuncture in treating oculomotor paralysis
LI Shouqing
Objective
To analyze the traditional Chinese medicine combined with acupuncture on the application value and safety of oculomotor nerve palsy patients.
Methods
60 cases of oculomotor nerve palsy patients were randomly divided into two groups,the efficiency of two groups of patients,the blood vessel,the quality of life were compared.
Results
The total efficiency of the treatment group was 93.3%,quality of life score (76.88±8.65) was significantly higher than the control group 66.7%,(67.29±8.30) %.The control group had no adverse reaction in the observation group,2 cases had mild nausea and no influence on the treatment.
Conclusion
Acupuncture combined with traditional Chinese medicine can effectively and improve the quality of life in patients with oculomotor paralysis,and the application value is remarkable
2017 Vol. 40 (5): 330-332 [
Abstract
] (
154
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333
Clinical observation of iris hooks combined with 2-eyelet modified capsular tension ring in the treatment of severe zonular dysfunction
JIANG Yaqin, GAO Jing, ZHANG Min, ZHANG Canwei, HUANG, Xudong
Objective
To evaluate the outcomes of iris hooks and 2-eyelet modified capsular tension ring (2L-MCTR) for treating severe zonular dysfunction of various causes, and explore the advantages and disadvantages,surgical skills and complications.
Methods
The study population comprised 11 eyes (7 patients) with severe zonular compromise that underwent capsular bag fixation with 2-eyelet modified capsular tension ring (2L-CTR) and in-the-bag intraocular lens (IOL) implantation.The postoperative follow-up was 1 to 3 years.UCVA(uncorrected visual acuity), BCVA (best corrected visual acuity), IOP (intraocular pressure) and condition of posterior capsule opacification were evaluated.Ultrasound biomicroscopy (UBM) was performed to observe the positions of IOL,MCTR and the relationship with other anterior segment organizations of eyes.
Results
Best corrected visual acuity (BCVA)＞0.3 occurred in all of 11 eyes.There were 7 eyes with best corrected visual acuity (BCVA)＞0.8 and 3 eyes with best-corrected visual acuity (BCVA)＞0.5.BCVA in one eye with retinal contusion was 0.3.IOL was implanted in the ciliary sulcus in one eye.UBM showed that all the modified capsular tension ring and intraocular lens were in the capsular bag.Conclusions The iris hooks can provide excellent intraoperative capsular stability and secure manipulation during operation.MCTR can ensure the intraocular lens central position in the capsular bag and can maintain its long-term stability, and it is helpful and effective for avoiding dislocation of the IOL due to progressive weakening of the zonular fibers.
2017 Vol. 40 (5): 333-337 [
Abstract
] (
172
)
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337
The research about the relationship between Erythropoietin level change of patientswith renal anemic hemodialysis and hemoglobin variability
WAN Hua, LI Rui, ZI Liying
Objective
To discuss the influence of Erythropoietin (EPO) level change for hemoglobin mutation in maintenance hemodialysis anemia patience.
Methods
The information of renal anemia patience for maintenance hemodialysis was collected to observe the influence of hemoglobin mutation continuously for 12 months by checking hemoglobin level once per month and changing EPO amount based on hemoglobin fluctuation (+/- 15% EPO amount).
Results
The sufficiency of maintenance hemodialysis influenced hemoglobin mutation and control rate.It was based on the result that the hemoglobin level of 30% patience maintained within control range during the 6 months period while 17% of them had hemodialysis fluctuation≤10 g/L.
Conclusion
EPO level change can reduce hemoglobin mutations and maintain the stability of hemoglobin.
2017 Vol. 40 (5): 337-339 [
Abstract
] (
125
)
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340
The effects of tea leaves on learning,memory and cholinergic system in aged mice
XU Yong, LI Jinlian, WANG Guihua, LUAN Haiyun
Objective
To investigate the effects of 3 kinds of tea extract on learning and memory,and the effects on cholinergic nerve function in natural aging mice.
Methods
Eighty Kunming mice were randomly divided into 5 groups: control group,model group,green tea extract group,Qimen black tea extract group and Ya'an black tea extract group.Three-month-old mice were used in the control group,and the other groups were given 16-month-old mice.At the end of fourth week,morris water maze test analysis system was used to detect changes in learning and memory abilities of mice,and the activity of SOD,GSH and MDA in brain,the activity of ChAT in hippocampus,respectively.
Results
The 3 tea extract group mice displayed promote of learning and memory ability in Morris water maze test.The mice in the tea group spent significantly less time swimming towards the former position of the hidden platform compared control,and crossed the former location of the platform significantly less frequently than controls.The activities of SOD,GSH-PX and MDA in the brain were significantly increased in the tea group,and the activity of ChAT in the hippocampus was increased.
Conclusion
Tea extract can improve the spatial learning and memory ability of aging mice,and its mechanism may be related to enhancing the function of the central cholinergic system.
2017 Vol. 40 (5): 340-342 [
Abstract
] (
131
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343
Change of TNF-α in the spinal cord of SOD1-G93A transgenic mice
HAN Xiaofeng, QI Yuying, WANG Yuan, MA Wenbin, WANG Xuezhen
Objective
To observe the change of TNF-α in the lumbar and thoracic spinal cord of SOD1-G93A transgenic mice at different stages and discuss the relationship between and progression of amyotrophic lateral sclerosis (ALS).
Methods
The level of TNF-α and TNF-α mRNA was analyzed by ELISA and RT-PCR at presymptomatic,symptomatic and end stages of SODl-G93A transgenic mice.
Results
Increasing TNF-α and TNF-α mRNA appeared at presymptomatic stage in the lumbar and thoracic spinal cord of SODl-G93A transgenic mice,and became obvious at symptomatic stage and reached the maximum at end stage.
Conclusion
TNF-α proliferates markedly with the progression symptom of SODl-G93A transgenic mice.TNF-α mediated neuroinfalammation, play an important role in the pathophysiology of ALS.
2017 Vol. 40 (5): 343-346 [
Abstract
] (
231
)
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346
The 5-Year survival rate of patients with pregnancy-associated breast cancer after therapeutic termination of pregnancy:a Meta-analysisWANG Hong LIU Kuikui WANG Hui
WANG Hong, LIU Kuikui, WANG Hui
Objective
To evaluate the 5-year survival rate of patients with pregnancy-associated breast cancer after therapeutic termination of pregnancy compared with those who continued the gestation,so as to provide an evidence for clinical practice.
Methods
This project utilized meta-analysis.Computer and manual retrieval was conducted to search literatures on cohort studies comparing the two methods of treatment.RevMan 5.3 software was used for statistical analyses.
Results
5 cohort studies were retrieved out. Meta-analyses showed that there was no significant difference between the two methods[
RR
=1.00,95% CI(0.69～1.45),
P
=0.99＞0.05].Subgroup analysis by TNM staging showed no significant difference,either.In StageⅠ,
RR
was 0.99, with 95% CI(0.55～1.76),and
P
was 0.83. In StageⅡand Ⅲ,[
RR
0.95,95% CI(0.46～1.95),
P
=0.62] and[
RR
0.88,95% CI(0.25～3.10),
P
=0.67],respectively.
Conclusion
Termination of pregnancy demonstrated no significant improvement for the prognosis of the patients with pregnancy-associated breast cancer.While, more large-sample cohort studies are needed to confirm the conclusion.
2017 Vol. 40 (5): 346-349 [
Abstract
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173
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350
The effect of psychological intervention on anxiety and depression in patients with brain injury:a Meta-analysis
JIANG Zhenzhen, XU Hongmei, WANG Meilin, LI Xiaoli,SU Xinyang
Objective
To explore the effect of psychological intervention on anxiety and depression in patients with craniocerebral injury for the method of a systematic review of evidence-based medicine.
Methods
Data were collected from the Cochrane Library,PubMed, Embase,China Biological Medicine Database,CNKI, Wanfang Database and VIP from the establishment of the databases to January 2017 to collect the correlation literature about the effect of psychological intervention on anxiety and depression in patients with brain injury.According to the inclusion and exclusion criteria,data were extracted for quality evaluation.RevMan 5.3 software could be used to conduct Meta-analyze for each indicator.
Results
In the end, there were 5 articals had been involved .The results showed that 5 studies were low qualified.A total of 400 people were enrolled,Psychological intervention group of 200 cases and the Control group of 200 cases. There were significance difference between psychological intervention group and Control group. The Psychological intervention group patients with anxiety symptoms score (95％Cl -1.17～-0.71,Z=8.07,
P
＜0.001), the Psychological group with depression symptoms score (95%Cl -1.91～-1.44,
Z
=13.88,
P
＜0.00001).
Conclusion
Psychological intervention can reduce the anxiety and depression of patients after craniocerebral injury, Improve the mental health and Improve the quality of life. It is worth to use clinical.
2017 Vol. 40 (5): 350-353 [
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139
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354
The applied research of moderate-length catheter in the pediatric intravenous infusion
JI Xin GAO, Junfang, LIU Xiujing, ZHU Meiyu, XING Yuejun
Objective
To determine the effectiveness of moderate-length catheter's clinical application in pediatric ward by using micro introducer scabbard technology.
Methods
268 children patients were randomly divided into two groups,the control group (137 cases) using BD indwelling needle for iv infusion,the experimental group (55 cases) using moderate-length catheter for iv infusion,the phlebitis after catheter uproot, fluid exudation,plugging rate, infection rate and the satisfaction of parents were compared between the two groups.
Result
Compared with the control group,the incidence of phlebitis and fluid exudation,plugging,infection were significant decreased, the satisfaction of parents were higher than the control group.
Conclusion
Choosing moderate-length catheter for infusion can decrease venous complications, improving the parents satisfaction.
2017 Vol. 40 (5): 354-356 [
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97
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