Home  |  About Us  |  Editorial Board  |  Instruction  |  Subscribe  |  Advertising  |  Messages Board  |  Contact Us  |  中文   Office Online Online Submission Peer Review Office Work   Journal Online    Forthcoming Articles    Current Issue    Archive    Read Articles    Download Articles    Email Alert     2017 Vol. 40, No. 2 Published: 2017-04-15   81 Characteristics of obstructive sleep apnea hypopnea syndrome with different levels of hypoxia LIU Tingting, ZHAO Yan, SUN Yunliang, LIU Jianghua, YANG Jiabin, ZHANG Kai, HAN Fang Objective In order to analyze the clinical characteristics and the characteristics of polysomnograpgy in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) at night.Methods 289 OSAHS patients were grouped according to the condition of lowest oxygen saturation,of which 69 cases of mild group,lowest oxygen saturation at 85%～90%,moderate group in 73 cases,lowest oxygen saturation at 80%～85%,147 cases of severe group,lowest oxygen saturation at ＜80%.Clinical characteristics of different lowest oxygen saturation in patients with OSAHS including age, body mass index (BMI), neck circumference,Epworth sleep scale(ESS),oxygen desaturation index (ODI),apnea hypopnea index (AHI),total apnea time,the longest apnea time and total hypopnea time and the longest hypopnea time,non-rapid eye movements(NREM) stage 1,NREM stage 2,NREM stage 3 and rapid eye movements(REM) sleep the percentage of total sleep time period was analyzed.Results The 3 groups in age,ESS score,total hypopnea time and the longest hypopnea time,REM and NREM stage 1 during the between BMI and ODI,AHI,total apnea time, the longest apnea time,NREM stage 2 and NREM stage 3 there are obvious differences, performance was significantly higher than that of mild group and moderate group in severe group were BMI, ODI, AHI, neck circumference, total apnea time,the longest apnea time between the three groups were significantly different in severe group NREM stage 2 higher than in the mild group, severe group and mild group in a period of less than NREM stage 3.Conclusion The patients with BMI,neck circumference affects patients with the lowest blood oxygen saturation; hypoxia degree of patients with more severe patients,oxygen desaturation index and apnea index is higher,total apnea time,longest apnea time,NREM stage 2 longer,while the patients with deep sleep NREM stage 3 sleep time is short. 2017 Vol. 40 (2): 81-84 [Abstract] ( 116 ) HTML (1 KB)  PDF  (0 KB)  ( 39 ) 85 Comparison the postoperative wound reaction of the lumbar spondylolithesis treatment by OLIF and PLIF LIU Xin, SUN Zhaozhong, LI Rui, REN Jiabin, ZHENG Zhenyang, LI Lu Objective To explore and comparison the trauma responses of the lumbar fusion between oblique vertebral body (OLIF) and traditional PLIF technique for the treatment of lumbar olisthe disease.Methods Fifty-two patients were enrolled by the entry criteria between August 2014 and February 2015 in our hospital,and were assigned to using the oblique vertebral fusion between (OLIF group,n=17) and posterior lumbar interbody fusion (PLIF,n=35).The length of skin incision,intra-operative blood loss,and post-operative hospital stay were recorded,as well as the serum levels of C-reactive protein (CRP) and creatine kinase(CK)were measured before and the same time after operation.The pain severity of incision in postoperative 1 d, 2 d, 3 d was evaluated by visual analog scale (VAS).And at the same time to evaluate lumbocrural painpre of operative and postoperative 1 d, 2 d, 3 d.Results There was no statistically significant difference in the general information in both groups (P＞0.05),after analysis,the lumbocrural pain VAS score of the two groups were lower than the preoperative and postoperative,there was no significant difference between the two groups (P＞0.05),but in the incision length,intra-operative blood loss,hospital stay in,patients in group A were lower than group B,there are statistically significant difference (P＜0.05).The serum levels of CRP and CK were measured 12 h,24 h and 48 h of after operative in group A were lower than group B, with statistical significance (P＜0.05).Two groups of postoperative 1~3 d incision pain VAS score were falling,the postoperative 1~3 d VAS score between the group A and B were differences,and A significantly lower than B.they were statistically significant (P＜0.05).Conclusion Two groups of surgical way to treat lumbar olisthe disease all can obtain satisfactory curative effect.But OLIF surgery not only can ensure the curative effect,also have the advantage of less bleeding,local symptom is light,quick recovery, cause tissue damage and system traumatic stress reaction is lighter. 2017 Vol. 40 (2): 85-88 [Abstract] ( 156 ) HTML (1 KB)  PDF  (0 KB)  ( 74 ) 89 Meta-analysis on effect of compound ganglioside injection in treating cerebral infarction GUO Lisha, LIN Feixue, WANG Xianbin, CHANG Lujie, ZHENG Jinghui, DU Xuqiang Objective To systematically evalutate the clinical efficacy and safty of compound ganglioside injection(GM1)in treating cerebral infarction(CI) of adults.Methods Computer retrievals were made in CNKI,VIP,Wanfang Data, Medline, Embase and relevant literature references(before October 2015),and manual retrievals were made for journals and conference papers.We collected randomized controlled trials concerning compound GM1 in the treatment of CI.The quality of included references was evaluated according to literatures recommended by Cochrane Handbook.RevMan 5.3 software was applied in the statistical treatment. Finally, a total of 36 randomized controlled trials were included,covering 2 076 patients (including 1 041 patients in the compound GM1-treated group and 1 035 patients in the control group ).Results Meta-analysis results showed that the routine treatment combined with compound GM1 could improve the treatment efficiency of CI [RR =1.28, 95% CI(1.23~1.34)],improve the cure rate [RR=1.46, 95%CI(1.28~1.67)] and reduce the neurological deficit scores [MD =-9.08, 95% CI(-11.61~-6.54)] with statistical differences.Of the included studies 5 cases of skin rash appeared,7 cases of alanine Aminotransferase (GPT) increased.After stopping drugs,these above disappeared without damage to liver and kidney function.Conclusion So far,limited evidences in this study proved that the application of compound GM1 in the treatment of CI can enhance the clinical efficiency. However,because of the low quality of the included trials,more well-designed and large scale multi-center randomized controlled trials shall be made in the future. 2017 Vol. 40 (2): 89-93 [Abstract] ( 157 ) HTML (1 KB)  PDF  (0 KB)  ( 45 ) 94 Clinical analysis of vitiligo treated with 308 nm excimer light LI Juan, SUN Li, ZHANG Yujie Objective To analyze the related factors of 308 nm excimer light in the treatment of vitiligo.Methods Topical treatment with 308 nm excimer light was performed 1 times every 4 days,with a course of treatment for 10 times.Results The total effective rate was 90.16% and the significant effective rate was 78.69%.The total effective rate and the significant effective rate of children were higher than those of the aged (over 60 years old).The shorter the course of disease was,the higher were total effective rate and the significant effective rate.There was no significant difference in the total effective rate and the significant effective rate in the period of the disease.The total effective rate and the significant effective rate of the parts was, the head and face ＞ the neck ＞ Head face ＞ Trunk ＞ Limbs ＞ Hands and feet ＞ the mucosa.The incidence of adverse reaction was 47.54%.Conclusion 308 nm excimer light in the treatment of vitiligo was safe and effective,the patient's age,course of disease,the location have an impact on efficacy,but stage had no significant effect. 2017 Vol. 40 (2): 94-96 [Abstract] ( 148 ) HTML (1 KB)  PDF  (0 KB)  ( 84 ) 97 The analysis of effect and safety of tacrolimus combined with 311 nm narrow-spectrum uvbrays to treat palmoplantar pustulosis WANG Xuehong, XUE Xinxin, DONG Yanxia, XU Wen, MA Qiang Objective To the efficacy and safety of using the method of tacrolimus combined with 311 nm narrow-spectrum uvb rays to treat palmoplantar pustulosis (PPP).Methods A total of 99 patients with moderate or severe PPP were enrolled in the study and were randomized into either the treatment group or control group.The treatment group used the method of 0.1% tacrolimus ointment combined with 311 nm narrow-spectrum uvb rays to treat PPP,the control group only for narrow spectrum uvb rays irradiation.After treatment for 2 weeks,4 weeks,6 weeks,8 weeks to determine efficacy,record adverse reactions.Results After treatment of 8 weeks the total scores of skin findings at the last observation were (2.61±1.48) in the treatment group and (3.75±1.99) in the control group,the difference was statistically significant. In particularly,the score of pustules/vesicles drastically decreased in the treatment group.In terms of safety,the incidence of adverse reactions in the treatment group and control group were 13.7% and 8.3%.There was no difference in the incidence of adverse reactions.Conclusion The treatment of tacrolimus combined 311 nm narrow-spectrum uvb rays is effective and highly safe in the management of PPP. 2017 Vol. 40 (2): 97-99 [Abstract] ( 142 ) HTML (1 KB)  PDF  (0 KB)  ( 56 ) 100 Clinical significance of pleural effusion LDH in patients with lung adenocarcinoma complicated with malignant pleural effusion JIAN Jinbo, ZHANG Luyan, YU Zeshun, NING Fangling Objective To discuss clinical significance by measuring the effusion level of lactate dehydrogenase(LDH) in patients with lung adenocarcinoma complicated with malignant pleural effusion.Methods All of 39 cases of hospitalized patients with lung adenocarcinoma complicated with malignant pleural effusion were subjected to closed drainage of the thoracic cavity using a central venous catheter, and cisplatin reperfusion of the thoracic cavity.The patients with EGFR mutations were subjected to EGFR-TKI treatment.Additionally,the others who no EGFR mutations were accpeted conventional chemotherapy.Lactic acid substrate rate method was performed before treatment in order to monitor levels of pleural effusion LDH. All patients were followed up to after the end of treatment.Results According to the receiver operating characteristic (ROC) curve,when the cut-off value was 436.7 U/L,the sensitivity was 91.7% and the specificity was 59.3%. The mPFS of low pleural effusion LDH (≤436.7 U/L) was higher than the high pleural effusion LDH (＞436.7U/L) in patients (P＜0.05),the difference was statistically significant.There is no significant difference of mPFS between the conventional chemotherapy group and EGFR-TKI treatment group(P＞0.05).Multivariate Cox regression analysis indicated that the level of pleural effusion LDH was an independent risk predictor for prognosis.Conclusion Detection of pleural effusion LDH in the prognosis of patients with lung adenocarcinoma complicated with malignant pleural effusion was important. 2017 Vol. 40 (2): 100-102 [Abstract] ( 136 ) HTML (1 KB)  PDF  (0 KB)  ( 60 ) 103 Influences of sustained intervention on clinical effects of perioperative prophylactic use of antibiotics ZHANG Min, ZHAO Ting, YU Lihong Objective To analyze the use of antibiotics during perioperative period in our hospital,and to provide reference for administration of antibiotics application.Methods 3792 surgical cases from January 2013 to December 2015 were randomly selected to evaluate the perioperative use of antibiotics.The rationality of antibacterial drug indications,drug selection,usage and dosage,medication time,duration were avaluated.Results From 2013 to 2015,the perioperative antimicrobial of the rational utilization rate respectively 48.2%,78.9%,90.1%.Remarkable management effect was obsvered.Conclusion The perioperative antimicrobial utilization in our hospital is more and more standardized,but a small part of problem such as excessive use of antibiotic in clean surgical site during perioperation,long duration of antibiotics prophylaxis still exists.The rational utilization of antimicrobial drugs required by the Ministry of Health should be strict implemented in order to ensure the drug safety,economy and efficacy for patients. 2017 Vol. 40 (2): 103-106 [Abstract] ( 149 ) HTML (1 KB)  PDF  (0 KB)  ( 60 ) 107 Hypnotic effect of chloral hydrate enema in infancy caries during dental treatment ZHENG Lixia, ZHANG Jinlong, WEI Wei, WANG Chunyan, ZHAO Han, WANG Qingshan Objective To observe the clinical sedative effect using 10% chloral hydrate enema during dental treatment for different age groups which have suffered from caries.Methods One hundred and fifty-six cases of dental treatment infants who had got caries were included in this study,they were divided into two groups A and B by age, and were given 10% chloral hydrate enema before the dental treatment respectively.To observe and compare the two groups of children with the drug effecting time,treatment operation time,sleeps maintain time,success rate and adverse reactions.Results Group A showed shorter time than group B in enema working time,and group A showed longer time than group B in maintain time of sedation,with significant difference.The two combination metered success rate is 85.26% in clinical sedative effect, and group A is 53.95% while group B is 20.00% in significant efficiency,there is statistically significant difference;Group A (93.42%) had higher success rate than group B (77.50%),with significant difference.Conclusion Hypnotic effect by 10%chloral hydrate enema in infancy caries during dental treatment is safe and reliable,and has high success rate.The smaller age has the faster drug effecting time,the longer sleep time,the higher efficiency and success rate. 2017 Vol. 40 (2): 107-109 [Abstract] ( 133 ) HTML (1 KB)  PDF  (0 KB)  ( 55 ) 110 The research about value of endoscopic ultrasonography diagnosis and minimally invasivetreatment of upper gastrointestinal submucosal tumors LIU Hongye, LIU Yipin Objective To evaluate the diagnostic value of endoscopic ultrasonography (EUS) and endoscopic therapies under the guidance of EUS in upper gastrointestinal submucosal tumors.Methods Sixty-seven patients with protruding lesions of upper gastrointestinal submucosal tumors were examined by EUS and CT.And then the specimen was obtained through endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) for the biopsy to compare with the diagnostic accordance rate of EUS and CT.Results The accuracy of EUS (88.1%) was significantly higher than that of CT (26.9%).EUS could clearly visualize the structure of the gastrointestinal wall,and accurately determine the origin of the tumor, but in the detection of infiltrating peripheral tissues and distant lymphnode metastasis,CT was superior to EUS.Conclusion EUS is an effective and reliable diagnostic method not only for accurately determining the size, origin and the location of upper gastrointestinal submucosal tumors but also for guiding minimally invasive therapy. 2017 Vol. 40 (2): 110-113 [Abstract] ( 75 ) HTML (1 KB)  PDF  (0 KB)  ( 86 ) 114 Clinical curative effect and safety assessment of synchronization radiotherapy and sequentialchemotherapy on older patients with advanced gastric cancer WANG Xiangfen, ZHENG Yanping, ZHANG Zhen, WANG Yulin, GAO Minglan Objective To study the clinical curative effect and safety assessment of synchronization radiotherapy and sequential chemotherapy on older patients with advanced gastric cancer.Methods 126 cases of elderly patients with advanced gastric cancer were selected,randomly divided into experimental group and the control group (n=63).The control group was given 5-fluorouracil joint dorsey after four to six cycles of chemotherapy with cisplatin and radiotherapy alone.The experimental group was given oxaliplatin into joint bevacizumab and capecitabine for 2 cycles of chemotherapy and radiotherapy.The therapeutic effect,survival rate and local control of 1 year,3 years,5 years,complications of two groups were observed.Results The total effective rate (92.1%) of the experimental group was obviously higher than that of control group (79.4%);The 1 year,3 years,5 years survival rate (68.3%,55.6%,46.0%) of experimental group were significantly higher than the control group (55.6%,46.0%,34.9%).The 1 year,3 years,5 years of local control (77.8%,63.5%,47.6%) of experimental group were significantly higher than the control group (63.5%,47.6%,38.1%).The incidence of complications (14.3%) of experimental group was significantly lower than the control group (31.7%).Conclusion The synchronization radiotherapy given to the elderly patients with advanced gastric cancer can better control the condition, improving survival and reducing complications, which is relatively safe. 2017 Vol. 40 (2): 114-116 [Abstract] ( 150 ) HTML (1 KB)  PDF  (0 KB)  ( 44 ) 117 Effect identification of GALNT12 on the growth of acute myeloid leukemia cells ZHANG Qiang Objective To explore the effect of GALNT12 expression on the growth of acute myeloid leukemia cells.Methods The relevant data in the acute myeloid leukemia (AML) patients' database were analyzed to clearly explain the relationship between the expression level of GALNT12 mRNA and AML patients' survival.GALNT12 shRNA lentiviral vector was constructed and lentivirus containing GALNT12shRNA was packaged as a tool to construct GALNT12 silenced leukemia THP-1 cell line. The THP-1 cell line infected by the Scramble lentivirus was used as a control group to observe the difference in the growth of THP-1 cells between the silenced GALNT12 and the control group. GFP-positive cells were collected by flow cytometry and used to observe the effect of GALNT12 on the growth of AML cells.Results The expression of GALNT12 was negatively correlated with the survival cycle of AML patients and GALNT12 was highly expressed in acute myeloid leukemia THP-1 cell line. This study successfully constructed GALNT12 silenced leukemia THP-1 cell line.When GALNT12 shRNA1 interferenced THP-1 cells compared with shScramble,the growth rate was significantly slower.Conclusion The expression of GALNT12 can promote the growth of acute myeloid leukemia cells and promote the development of acute myeloid leukemia. It also adds new content to the effective molecular target for the treatment of acute myeloid leukemia. 2017 Vol. 40 (2): 117-119 [Abstract] ( 112 ) HTML (1 KB)  PDF  (0 KB)  ( 83 ) 120 Clinical evaluation of efficacy of three kinds of desensitizer for prevention of dentin hypersensitivity after deep caries treating TIAN Hongxu, HOU Yudong Objective To evaluate the efficacy of three kinds of desensitizer for the prevention of dentin hyper-sensitivity in deep cavities.Methods The 195 teeth of 114 cases with deep caries were divided into three groups randomly,and before curable resin filling treated with three different desensitizers as Oravive desensitizer,Gluma desensitizer and calcium hydroxide respectively. Effective rates of the three agents on teeth were examined immediately,one month and three months after the treatment.Effective rates were compared in three groups.Results The efficacy of the Oravive and Gluma groups were obviously higher than that in calcium hydroxide group (P＜0.01).There was no significant difference between Oravive and Gluma groups (P＞0.05).After three months of the treatment,Oravive group has significantly higher than Gluma and calcium hydroxide groups (P＜0.01).But the efficacy of Gluma was similar at that of calcium hydroxide group.Conclusions Oravive desensitizer is an effective desensitizer preventing dentin hypersensitivity of post-filling complications in deep caries. 2017 Vol. 40 (2): 120-122 [Abstract] ( 238 ) HTML (1 KB)  PDF  (0 KB)  ( 86 ) 123 The study of orthodontic treatment on root resorption of nonvital pulp teeth and vital pulp teeth WANG Yanli, GAO Yuguang Objective To investigate the effect of orthodontic treatment on the absorption of nonvital pulp teeth and vital pulp teeth in patients of different age and gender.Methods 60 cases of patients who had been treated by fixed orthodontic appliance for not less than 12 months were randomly chosen with panoramic radiograph.At least one tooth of each patient's dentition had been treated with root canal treatment.The root length of the same patient's nonvital-pulp teeth and the contralateral vital-pulp teeth were measured before and after treatment,and the data were statistically analyzed.Results There was no significant difference in root resorption of nonvital and vital pulp teeth after orthodontic treatment.There was no significant difference in root resorption between different ages in males or females.There was significant difference in root resorption of non-vital pulp teeth between different ages in male or female during orthodontic treatment.Conclusion Orthodontic treatment didn't increase the risk of root resorption of vital pulp teeth.Orthodontic treatment had significant effects on root resorption of different age groups. 2017 Vol. 40 (2): 123-125 [Abstract] ( 113 ) HTML (1 KB)  PDF  (0 KB)  ( 45 ) 126 The diagnostic value of ultrasonography in the diagnosis of benign and malignant thyroid nodules DAI Chengcheng, LIU Xinjiang Objective To investigate the value of ultrasonic elastography (UE) in the differential diagnosis of suspected malignant thyroid nodules.Methods 52 cases of 98 thyroid nodules were examined with conventional ultrasonography,observe the nodular morphology,boundary,internal echo,rear echo attenuation nodules, aspect ratio,acoustic halo, internal calcification,distribution of blood,peripheral lymph node enlargement and other features;then the elastic imaging,the elastic image is divided into 0~IV.The results of ultrasound diagnosis and pathological results were compared.Results the results of ultrasound elasticity imaging:0~II grade 78 nodules (74 cases of benign,4 cases of malignant);III,IV grade a total of 20 cases (15 cases of malignant, 5 cases of benign).Based on the elastic stage IV~V is highly malignant and forecasting index,the sensitivity,specificity,positive predictive value, negative predictive value, accuracy rate of 78.9%,93.7%,75%,94.9%,90.8%,was significantly higher than that of conventional ultrasound and color Doppler energy ultrasound (P＜0.05).Conclusion ultrasound imaging is helpful for the differential diagnosis of benign and malignant thyroid nodules. 2017 Vol. 40 (2): 126-127 [Abstract] ( 149 ) HTML (1 KB)  PDF  (0 KB)  ( 69 ) 128 The clinical application of low-dose MSCT scan in the review of solitary pulmonary nodules DUAN Yinzhong, BIAN Jia, LI Quan, LIU Hairong, ZHANG Lin Objective To explore the application value of low mAs combined with adaptive statistical iterative reconstruction (ASIR) technique in the review of solitary pulmonary nodules (SPN).Methods 86 cases of patients with solitary pulmonary nodules were regularly followed up after 3 months, respectively for low mAs combined with ASIR of low dose scanning and routine scanning, the nodule size,radiation doses were compared between the two groups.Results The image quality score of low dose group was lower than that of the conventional group,but was no of statistically significant difference of qualified rate between them,the two groups of images could be found solitary pulmonary nodule s sensitive. There was no significant difference of the size of the lesions between the two groups. Two groups of CTDIvol, DLP had significant difference.Conclusion Low mAs combined with ASIR technique can reduce the radiation dose,which doesn't affect the detection and display of solitary pulmonary nodules,and have some clinical significance. 2017 Vol. 40 (2): 128-130 [Abstract] ( 123 ) HTML (1 KB)  PDF  (0 KB)  ( 44 ) 131 Clinical research about the treatment of hyperlipidemia with xuezhining mixture DONG Chunmei, WANG Binsheng Objective To observe the effect of xiezhining mixture on the blood lipid,blood rheology of patients with hyperlipidemia.Methods 120 patients on the hyperlipidemia diagnosis standard were randomly divided into xiezhining mixture group and simvastatin group.Each group was 60 cases,xiezhining mixture group was placed on oral xiezhining mixture,simvastatin group to give oral simvastatin.TC,TG,LDL-C,HDL-C and the change of blood rheology in two groups before and after treatment were observed,comparative analyzed and statistical processed.Results The blood lipid and blood rheology of two groups before treatment had no significant difference.Compared with before treatment,TG,TC and LDL-C of the two groups after treatment were significantly lower,HDL-C were significantly increased,and all the indexes of hemorheology were lower.The effect of xiezhining on lowering TG,LDL-C and increasing HDL-C level was better than that of simvastatin group.The effect of xiezhining on decreasing whole blood viscosity and red blood cells deposited was better than that of simvastatin group.Conclusion Xiezhining mixture had good curative effect on regulating blood lipid and blood rheology. 2017 Vol. 40 (2): 131-133 [Abstract] ( 129 ) HTML (1 KB)  PDF  (0 KB)  ( 68 ) 134 Study of bacteriostatic action in vitro of compound sanhuang tincture DING Changling, TIAN Honggen, ZHANG Xuemei, FAN Qizhong Objective To study the bacteriostatic action invitro of two kinds of preparation technology of compound Sanhuang tincture in vitro.Methods To use the bacterial inhibition ring assay and the pancreatic dairy soy peptone liquid medium diluted method to do minimal inhibitory concentration (MIC) and minimal bacterieidal concentration (MBC) test for Escherichia coli,Staphylococcus aureus,Pseudomonas aeruginosa,and Candida albicans.Results Two preparation process of compound Sanhuang tincture has strong bacteriostatic and bactericidal activity of the Staphylococcus aureus,Pseudomonas aeruginosa and Candida albicans,Staphylococcus aureus is more sensitive.Conclusion The compound sanhuang tincture had remarkable bacteriostatic action in vitro. 2017 Vol. 40 (2): 134-136 [Abstract] ( 165 ) HTML (0 KB)  PDF  (0 KB)  ( 59 ) 137 Improvement effect of non invasive positive pressure ventilation combined with integrated care on acute left heart failure CHEN Hanxia, LI Dechang, FENG Yelyu Objective To investigate the effect of Non Invasive Positive Pressure Ventilation (NIPPV) combined with integrated care on acute left heart failure (ALHF).Methods There were 109 cases of acute left heart failure patients in our hospital from January 2014 to November 2015,according to the actual situation of patients,and based the different treatment methods,whom were divided into group control (36 cases),group NIPPV (39 cases),and group (NIPPV+ Integrated Care) (34cases),in the control group received cardiac,diuretic and vasodilator drugs (such as cedilanid,katlex,nitroglycerin or sodium nitroprusside) treatment,while giving the nasal catheter oxygen 4-6L/min;in the group NIPPV given the drug therapy by NIPPV treatment,in the group (NIPPV+ Integrated Care),based on group NIPPV treatment,and carried out integrating care during treatment;Both the three groups treatment before and after treatment 2 hour,amino terminal B type natriuretic titanium precursor (BNP),heart rate (HR),respiratory rate (R),arterial blood (pH,PaO2,SaO2) and HAMA score were tested or recorded;and then using telephone or outpatient follow-up of 1 years, the health measurement scale (SF-36) score was evaluated the treatment effect of the two groups.Results Compared with before treatment,the three groups of R,HR and BNP,PaO2,SaO2 values were significantly improved at treatment after 2hour (P＜0.05),and the BNP,PaO2 value of both group NIPPV and group (NIPPV+ Integrated Care) were significantly better than the control group (P＜0.05),and th evalue PaO2 and SaO2 of group (NIPPV+ Integrated Care) were significantly better than group NIPPV;the 92.30% overall efficiency of the group NIPPV and 97.06% in group (NIPPV+ Integrated Care) were significantly better than that of the 86.11% in control group (P＜0.05),and both group NIPPV and group (NIPPV+ Integrated Care) before and after treatment of 2hour and HAMA scores after 1 years of follow-up (SF-36) scores were significantly better than the control (P＜0.05).Conclusions In the treatment of patients with acute left heart failure, NIPPV treatment combined with comprehensive care could be quickly correcting the hypoxia, and improving heart function, and reducing the incidence of complications, to some extent, it would be worth studying. 2017 Vol. 40 (2): 137-141 [Abstract] ( 132 ) HTML (0 KB)  PDF  (0 KB)  ( 60 ) 145 The experiment teaching satisfaction survey on the public business management professional inmedical universities in shandong province HE Xiaomin, ZHAO Yongjun, DU Qing, WU Xiaona Objective To analyze the main affecting factors of laboratory using and experimental teaching satisfaction,and sought feasible solutions on basis of understanding the experiment courses about the public business management major in medical universities of Shandong province.Methods In 300 public management professional students as an object in Shandong Province Binzhou medical university and Weifang medical university,to carry out the questionnaire survey With the method of self-made questionnaire and the interview,then analyzed the laboratory using and teaching satisfaction by using of statistical methods and t test statistical methods.Results The satisfaction level was general to the professional laboratory using and experimental teaching, it was the lowest about laboratory hardware and software equipment satisfaction and the satisfaction difference was obvious between the different grade students(F=5.804,P=0.001).Conclusion Medical school should further strengthen the hardware and software investment and equipment updates to the public business management major in medical universities,updated the experimental teaching mode,gradually improved systemic and personalized construction of the experimental study,in order to satisfy the demands of students. 2017 Vol. 40 (2): 145-147 [Abstract] ( 147 ) HTML (0 KB)  PDF  (0 KB)  ( 77 ) Copyright © Editorial Board of 滨州医学院学报 Supported by:Beijing Magtech